Project Grant R21AI191005
- Federal Grant Award Summary The University of Pittsburgh received a $437,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 1, 2026 through January 31, 2028. The award funds research investigating Candida glabrata population diversity during gastrointestinal tract colonization and intra-abdominal candidiasis (IAC). The research addresses a critical gap in...
- Federal Grant Award Summary The University of Pittsburgh has received a $481,214 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 11, 2025, with completion targeted for August 31, 2027. This research project focuses on defining high-risk genomic groups within the Stenotrophomonas maltophilia complex, an increasingly important healthcare-associated pathogen that...
- Federal Project Grant Award Summary The University of Pittsburgh received a $430,760 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 10, 2025 through June 30, 2027. This award funds investigator-initiated biomedical research focused on developing immunological defense strategies against hospital-acquired Pseudomonas aeruginosa infections, particularly...
- Federal Grant Award Summary The University of Pittsburgh received a $371,141 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 6, 2025, with a completion date of July 31, 2030. The FUNDAMENTALS IN BIOINFORMATICS (FUNINBIO) program develops, deploys, and evaluates a continuing education curriculum designed to address bioinformatics skills gaps among post-doctoral scientists....
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pittsburgh a $189,146 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 5, 2025, through July 31, 2030. This five-year Research Career Development Program supports Dr. Glenn J. Rapsinski, MD, PhD, an Instructor of Pediatric Infectious Diseases at UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh...
- Federal Grant Award Summary The University of Pittsburgh received a $2.98 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 1, 2025, with a completion date of July 31, 2029. This research initiative investigates polyamine toxicity and resistance mechanisms in epidemic bacterial skin pathogens, specifically methicillin-resistant Staphylococcus aureus (MRSA) and...
- Federal Grant Award Summary The University of Pittsburgh has been awarded $719,195 under the Cardiovascular Diseases Research program (CFDA 93.837) administered by the National Heart, Lung, and Blood Institute (NHLBI), effective August 1, 2025, through April 30, 2030. This Project Grant funds research investigating the AIRSPACE CANDIDA COLONIZATION AND LUNG INJURY (AIRCCOLIN) initiative, which examines the mechanistic role of Candida species colonization in the lower respiratory tract of...
- Federal Project Grant Award Summary The University of Pittsburgh received a $452,835 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 2, 2026, with a completion date of January 31, 2028. This award funds research to develop novel nanobiologic therapeutics targeting innate immune memory responses in organ transplant rejection. The research focuses on investigating the...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pittsburgh a $437,250 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 25, 2025, with a completion date of June 30, 2027. This award supports research targeting host nuclear receptors to accelerate the resolution of methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs). The research will...
- Federal Grant Award Summary The University of Pittsburgh received a $109,076 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 14, 2026, with a completion date of August 31, 2028. This award supports research investigating post-transcriptional regulation mechanisms in T cells, with particular focus on identifying and characterizing an RNA-binding protein (RBP) involved in...
The University of Pittsburgh received a $437,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 1, 2026 through January 31, 2028. This award funds research to characterize genetic and phenotypic diversity of Candida parapsilosis (CP) populations in bloodstream infection cases, with particular focus on echinocandin antifungal resistance mechanisms. The research will analyze blood cultures from individual patients to identify previously unrecognized heteroresistance and tolerance phenotypes, challenging the traditional single-organism infection model and implicating specific genetic variants associated with antifungal treatment failures in candidemia cases. The project delivers scientific research services and biomedical research products that advance understanding of C. parapsilosis pathogenesis and antifungal resistance mechanisms. Since candidemia represents a significant healthcare burden in the United States with mortality rates approximately 20 percent despite frontline echinocandin treatment, this research directly supports NIAID's mission to improve clinical outcomes for infectious disease patients. The University of Pittsburgh's research infrastructure and capabilities in genomic analysis and infectious disease research enable the characterization of fungal population diversity and identification of novel resistance mechanisms that are not currently detected by standard clinical laboratory procedures.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $437.3k | 1/28/26 |