Project Grant R21AI194255
Award Date
8/1/25
Completion Date
7/31/27
Dollars Obligated
$458K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Farmington, CT 06030, USA
Similar Awards
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $135,258 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Virginia Polytechnic Institute & State University (Virginia Tech) on September 13, 2024. The grant will fund research to determine the biochemical features of Treponema pallidum peptidoglycan and the identity of released muropeptides, as well as elucidate the role of released peptidoglycan in the pathogenesis of...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) is for the development of a direct diagnostic test for infectious and congenital syphilis. The $260,760 award to the University of Victoria aims to create a test that: (1) exhibits high sensitivity and specificity at all disease stages; (2) can differentiate active versus past infections; (3) can differentiate syphilis from yaws;...
This federal Project Grant award, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund the development of a novel suite of local-level syphilis epidemiologic and economic models (LSEEM) across 40 U.S. cities with the highest syphilis diagnosis rates. The $1,550,917 award, spanning from July 2024 to May 2029, aims to assess the potential impact of scaling up existing syphilis control...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will provide $264,750 to the University of Washington to optimize methods for recovering the Treponema pallidum genome from diverse clinical specimens. The project aims to develop a tiling amplicon sequencing approach to improve the analytical sensitivity and scale of T. pallidum genome recovery, which is challenging due to the...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $698,349 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Pennsylvania State University to develop an integrated multiplexed diagnostic assay for detecting treponemal and nontreponemal antibodies to diagnose syphilis. The project aims to create a rapid, 10-minute point-of-care test that can simultaneously detect and semi-quantify both types of syphilis antibodies to better...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to optimize molecular polymerase chain reaction (PCR) testing for the detection of congenital syphilis. The $246,000 award, effective August 20, 2024 through July 31, 2026, will fund research to determine the optimal diagnostic specimen(s) and sampling strategy for PCR-based detection of Treponema pallidum in...
This $531,245 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will fund research by Yale University to structurally and functionally characterize the sorting platform component of the type III secretion system (T3SS) in Salmonella bacteria. Through a multidisciplinary approach involving bacterial genetics, biochemistry, microscopy, and cryo-electron microscopy, the research aims to...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $163,698 Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) to Magic Lifescience, Inc. in Mountain View, CA to develop a novel point-of-care molecular diagnostic assay for syphilis as part of a multiplexed genital ulcer disease (GUD) test panel. The key objectives are to: 1) develop a PCR-based, multiplexed molecular assay for Treponema pallidum (syphilis) and other GUD pathogens using giant...
This Project Grant award of $824,955.00 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to differentiate immune effector profiles and identify acute disease biomarkers in a guinea pig model of tick-transmitted spotted fever group rickettsiosis (SFR). The research aims to elucidate the immune response to spotted fever group rickettsiae and determine mechanisms underlying SFR development using a translational...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,663,244 project grant under CFDA 93.855, Allergy and Infectious Diseases Research, to President and Fellows of Harvard College (Harvard Medical School) on March 1, 2025. The project aims to characterize innate immune signaling pathways in the tick Ixodes scapularis, which is a vector for Lyme disease and other emerging infectious diseases. The research will combine cell culture-based methods with in vivo assays in...