This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $541,500.00 to support research on the relationship between calorie restriction, autoimmunity, and core body temperature. The research aims to investigate the effects of calorie restriction and thermoneutral housing conditions on circadian temperature profiles, long-term lupus disease progression, and gene expression in lupus mouse models. The goal is to understand how calorie restriction-induced reductions in core body temperature may contribute to its beneficial effects on autoimmunity. This research could have important translational implications for applying calorie restriction in humans, who often use behavioral thermoregulation to maintain thermoneutral conditions. The award period runs from June 17, 2025 to May 31, 2027 and will be conducted by the San Diego Biomedical Research Institute, a non-profit research organization.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $541.5k | 6/17/25 |