Project Grant R21AI193678
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $189,276 to Boston University Medical Campus under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 1, 2025, for a five-year project period concluding July 31, 2030. The project, titled "Characterizing Respiratory Syncytial Virus Burden and Prevention in the United States," delivers an agent-based mathematical modeling framework designed to assess...
- Federal Project Grant Award Summary Boston University Medical Campus received a $100,228 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective September 27, 2026, through May 31, 2029. This award supports investigator-initiated biomedical research to characterize the translational mechanism of Vesicular Stomatitis Virus (VSV) messenger RNA (mRNA), with the overarching objective of...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $815,378 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Trustees of Boston University, performing at Boston University Medical Campus in Roxbury, Massachusetts. The award, effective from May 1, 2026 through April 30, 2031, supports investigator-initiated research to identify and characterize high-affinity germline-encoded antibodies that...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston University Medical Campus a $204,375 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026 through March 31, 2028. This award supports investigator-initiated research focused on elucidating the mechanisms of filovirus messenger ribonucleic acid (mRNA) translation, with emphasis on Ebola virus and other highly pathogenic...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston University Medical Campus a $217,337 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 23, 2025, with completion targeted for June 30, 2027. The research project, conducted at Boston University's Massachusetts location, focuses on elucidating the role of the SARS-CoV-2 ORF9B protein in virus replication. The primary deliverables include...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston Children's Hospital a $800,557 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 19, 2026, with a completion date of January 31, 2031. This investigator-initiated research project is designed to identify and characterize the mechanisms by which Staphylococcus aureus, a gram-positive bacterial pathogen, manipulates inflammasome...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston Children's Hospital a Project Grant of $489,500 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 24, 2025, with a completion date of June 30, 2027. The award funds structural research aimed at determining the high-resolution three-dimensional structure of the full-length nucleocapsid (N) protein of Severe Acute Respiratory Syndrome Coronavirus 2...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston Children's Hospital $151,040 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on December 4, 2025, to support a project extending through July 31, 2028. This Project Grant funds basic science research investigating the regulatory mechanisms of a small regulatory RNA (sRNA) designated BECO in Pseudomonas aeruginosa, a gram-negative bacterium that causes serious...
- Federal Project Grant Award Summary Boston University Medical Campus received a $449,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 11, 2025, through May 31, 2027. The grant supports structural biology research on filoviruses, specifically examining the virion, nucleocapsid, and inclusion body structures of Lloviu virus (LLOV) and Ebola virus (EBOV). The...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Massachusetts General Hospital $364,484 through the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 25, 2025, to support research on soluble guanylate cyclase (SGC) pathway activation as a novel bronchodilation strategy for respiratory syncytial virus (RSV) bronchiolitis in pediatric populations. The research project, with an ultimate completion date of June 30, 2027,...
Boston University Medical Campus received a $245,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective May 1, 2026, through April 30, 2028. This award supports investigator-initiated basic biomedical research to identify and characterize non-canonical translation mechanisms utilized by pneumoviruses, specifically Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (HMPV), which cause significant respiratory infections in vulnerable populations including infants, elderly individuals, and immunocompromised patients. The research deliverables include the construction of reporter viruses to elucidate the role of viral 5' untranslated regions in promoting alternative translation pathways, generation of auxin-inducible degron-tagged cell lines targeting key eukaryotic initiation factors, and comprehensive characterization of RSV RNA-binding protein interactions. The project aims to identify viral and cellular factors enabling pneumoviruses to bypass conventional translation initiation pathways, with anticipated outcomes that will advance understanding of pneumovirus molecular mechanisms and potentially identify novel targets for antiviral therapeutic intervention.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $245.3k | 5/7/26 |