This $151,040 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate the regulatory role of the small regulatory RNA BECO on essential virulence factors in the pathogen Pseudomonas aeruginosa. The research aims to determine how BECO controls the expression of the Type III Secretion System and pyochelin biosynthesis genes, which are critical for P. aeruginosa virulence. The work will be conducted at Boston Children's Hospital, a non-profit pediatric medical research institution, and is expected to be completed by July 31, 2028. The findings from this research are anticipated to further the understanding of complex regulatory mechanisms governing P. aeruginosa virulence and could provide insights into developing new treatment strategies.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $0 | 6/5/25 | ||
| Not listed | $75.5k | 6/5/25 | ||
| Not listed | $75.5k | 6/5/25 |