Project Grant R21AI191624
- Federal Grant Award Summary Baylor College of Medicine received a $797,087 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 18, 2026, with a completion date of January 31, 2031. The grant funds research to identify the molecular mechanisms driving transovarial transmission (TOT)—the vertical transmission of pathogens from infected ticks to their offspring—using the...
- Federal Grant Award Summary Baylor College of Medicine received a $454,791 Project Grant award dated August 22, 2025, from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate gene regulation mechanisms in tick-borne relapsing fever spirochetes. The research will be conducted through July 31, 2027, at the institution's Texas location. The project focuses on elucidating the molecular mechanisms...
- Federal Project Grant Award Summary Baylor College of Medicine received a $160,500 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. The grant funds the development of a Rickettsia species isolate library derived from tick specimens collected in Texas and Belize. The primary deliverables include establishment of a curated bank of Rickettsia...
- Federal Grant Award Summary Texas A&M Agrilife Research received a $423,106 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. The award supports research to characterize the role of tick metalloprotease inhibitors in the transmission of Borrelia burgdorferi, the causative agent of Lyme disease, by blacklegged nymphal ticks. The research...
- Federal Project Grant Summary Baylor College of Medicine received a $461,187 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning April 1, 2026 and concluding March 31, 2028. The award funds a One Health epidemiological investigation into Leishmania transmission in two major Texas metropolitan areas: Houston and Dallas. The research will deliver integrated surveillance and...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $518,099 to the University of Maryland, College Park on July 17, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct biomedical research investigating cross-species signaling mechanisms in tick immunity and pathogen response. The research examines how the tick species Ixodes scapularis senses and responds to mammalian-derived factors, particularly...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $417,845 to the University of Nebraska Medical Center under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period from August 1, 2025, through July 31, 2027. The award supports the development and adaptation of an innovative in vitro organotypic human skin model designed to enable tick feeding and study the transmission and colonization of Borrelia...
- Federal Grant Award Summary Baylor College of Medicine received a $160,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 8, 2025, with a completion date of July 31, 2027. The grant funds development and validation of a novel TC-24 Enzyme-Linked Immunosorbent Assay (ELISA) test to evaluate post-treatment efficacy for Chagas disease, a neglected tropical disease endemic...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Tufts University School of Medicine a $165,000 project grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 1, 2025, with a completion date of June 30, 2027. This award funds the development of an improved transposon mutagenesis system for comprehensive genetic analysis of Borrelia burgdorferi, the causative agent of Lyme disease. The primary deliverables...
- Federal Grant Award Summary Yale University received a $461,375 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025 through June 30, 2027. The grant supports systematic identification of molecular interactions between Lyme disease bacteria (Borrelia burgdorferi) and its tick vector (Ixodes scapularis). The primary deliverable involves screening the ISCREAM (I....
Baylor College of Medicine received a $200,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 5, 2026, with completion scheduled for April 30, 2028. The grant funds research to unravel the vector ecology and genomic drivers of vertical transmission of relapsing fever Borrelia in populations of the argasid tick species Ornithodoros turicata. The project addresses significant knowledge gaps regarding infection prevalence in tick populations, transovarial transmission dynamics, and the molecular mechanisms that enable pathogen persistence and vertical transmission in acari (ticks). The research deliverables include comprehensive fieldwork across the United States and Mexico to characterize naturally infected O. turicata populations from diverse geographic regions, genomic analysis to identify genetic bases for vertical transmission capabilities, and identification of molecular targets for neutralizing acari-borne pathogens. By elucidating the biological and genetic mechanisms that facilitate pathogen maintenance in ticks, this research is intended to improve prediction of disease emergence and persistence while identifying intervention points to control relapsing fever transmission in vector populations.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $200.6k | 5/7/26 |