Project Grant R21AI190549
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $452,769 Project Grant awarded August 11, 2025, by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research project, which extends through July 31, 2027, investigates the efficacy of BDGR-49, a small-molecule therapeutic compound, in preventing long-term neurological sequelae...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $611,861 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 1, 2025, through August 31, 2030. The research project investigates chromosomal rearrangements in Aedes aegypti mosquitoes, the primary vector for dengue and Zika fever transmission. The funded...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $414,482 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 24, 2025, with completion targeted for June 30, 2027. The award supports research focused on developing an improved oncolytic virus therapy for glioblastoma treatment through directed evolution and...
- Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $422,355 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 23, 2025, with completion targeted for June 30, 2027. The research focuses on mechanistic studies of the GacS signaling histidine kinase from Pseudomonas aeruginosa, a nosocomial pathogen responsible for acute and...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $437,541 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and validate novel antisense therapeutics for treating Clostridioides difficile infection (CDI). The award, obligated on February 2, 2026, with a completion date of January 31, 2028, supports research into...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $832,818 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2030. The project, titled "Expanding Safe Water Access to Improve Health Outcomes in Appalachia: The Rural Water Filtration and Health (RWELL) Trial," addresses the...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $325,000 Project Grant from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Crop Protection and Pest Management Competitive Grants Program (CFDA 10.329). The award, obligated on September 15, 2025, with a completion date of September 14, 2027, supports the development of innovative disease forecasting tools to address fungal foliar diseases...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Virginia $3,047,991 on September 12, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a four-year biomedical research project extending through August 31, 2029. The research investigates paired receptor signaling mechanisms in natural killer (NK) cells for antiviral immunity, with particular focus on understanding how NK cell...
- Federal Grant Award Summary The University of Virginia received a $146,170 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective May 9, 2025 through April 30, 2030. This award supports the development of a global infectious diseases research framework designed to advance interdisciplinary collaboration among junior faculty and researchers engaged in global health...
- Federal Project Grant Award Summary The University of Vermont & State Agricultural College received a $438,983 Project Grant awarded July 8, 2025, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research project, spanning through June 30, 2027, focuses on investigating the biological impacts of a novel stable nucleocapsid protein dimer formation identified in SARS-CoV-2 variants (Beta,...
Virginia Polytechnic Institute & State University (Virginia Tech) received a $191,163 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 5, 2026, through January 31, 2028. The grant supports research on the transmission dynamics and pathogenesis of contemporary Mayaro virus (MAYV) strains, addressing the emerging public health threat posed by this arbovirus, which causes febrile illness and chronic joint pain in South America and has recently been detected in Haiti with evidence of urban transmission potential. The project deliverables encompass two primary research aims: (1) development of novel molecular tools and evaluation of transmission potential of contemporary Haitian MAYV strains using widespread mosquito vectors, including field-caught specimens; and (2) assessment of viral replication and virulence in human cells and mice models, determination of minimum infectious doses, and evaluation of complete transmission cycles between mice and mosquito vectors. These research products will advance understanding of MAYV's risk for expansion into North America through improved characterization of contemporary viral strains and their epidemiological potential, filling critical knowledge gaps that have limited risk assessment based on historical virus isolates.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $191.2k | 2/4/26 |