Project Grant R21AI190337
- Federal Grant Award Summary Penn State Milton S. Hershey Medical Center received a $267,704 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on April 3, 2026, with completion targeted for March 31, 2028. The grant funds development and deployment of a lateral flow point-of-care diagnostic device for rapid detection of Paenibacillus thiaminolyticus, a highly lethal bacterial...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Pennsylvania State University a Project Grant totaling $842,720 on April 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The five-year project, concluding March 31, 2031, will develop statistical models and methodologies to address critical information gaps in the global HIV response. The deliverables include longitudinal and spatial estimates of...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Trustees of The University of Pennsylvania a Project Grant totaling $803,591 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period February 3, 2026 through January 31, 2031. This research initiative focuses on developing shiv-infected rhesus macaques as a preclinical model for human immunodeficiency virus type 1 (HIV-1) broadly neutralizing antibodies...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pennsylvania a $891,410 Project Grant on August 14, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and test a personalized therapeutic HIV vaccine strategy. The research, scheduled for completion by July 31, 2030, focuses on designing individualized messenger RNA (mRNA)-lipid nanoparticle (LNP) delivered envelope immunogens to boost...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $627,483 Project Grant to the University of Pennsylvania under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2031. This research initiative will generate scientific knowledge regarding how environmental perturbations determine the duration of enteric viral infections, specifically examining murine astrovirus (MuAstV)...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Children's Hospital of Philadelphia $881,303 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 17, 2025, for a project extending through June 30, 2030. This Project Grant funds a comprehensive research initiative utilizing whole genome sequencing (WGS) and diagnostic allele (DA) surveillance to track pathogen transmission and infection dynamics in neonatal...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pennsylvania a $3.64 million Project Grant on July 8, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop immunoengineering strategies for durable control of human immunodeficiency virus (HIV) replication. The award supports a multi-project consortium through May 31, 2030, aimed at advancing chimeric antigen receptor (CAR) T cell therapy as...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Pennsylvania State University's Milton S. Hershey Medical Center a $425,004 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective July 7, 2025, with a completion date of June 30, 2027. This exploratory research project investigates the regulation of the cGAS-STING pathway by the RNF11 protein, focusing on understanding molecular mechanisms...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $489,500 to The Children's Hospital of Philadelphia Research Institute on June 11, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This two-year project, which extends through May 31, 2027, focuses on developing novel sequencing methodologies and analytical pipelines to identify and characterize intact human immunodeficiency virus (HIV) reservoir cells...
- Federal Grant Award Summary The University of Pennsylvania received a $434,375 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, with a completion date of July 31, 2027. This research project will investigate retroelement-mediated cis-regulation of embryonic hematopoiesis, specifically examining how retrotransposon-derived long terminal repeats function as...
Pennsylvania State University's Penn State Milton S. Hershey Medical Center received a $234,900 project grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2028. The award funds preclinical research investigating passive immunization strategies to prevent vertical papillomavirus (PV) transmission using a mouse papillomavirus model (MMUPV1). The research will characterize vertical PV transmission patterns associated with pregnancy timing and host immune status, and evaluate the protective efficacy of polyclonal and monoclonal neutralizing antibodies administered passively to offspring against oral infections in a dose and time-dependent manner. The project addresses the clinical need for novel interventions to prevent recurrent respiratory papillomatosis (RRP), an aggressive chronic disease in young children resulting from maternal-to-infant PV transmission, for which only invasive and repeated surgical treatments currently exist. Deliverables include characterization studies of vertical transmission mechanisms and efficacy data on antibody-based passive immunization approaches using established mouse papillomavirus infection models and assays, with findings intended to inform the development of preventive therapies for this pediatric disease.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $234.9k | 4/1/26 |