The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $433,125 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Ohio State University. The funding supports research to investigate the role of the influenza A virus (IAV) protein PB1-F2 in causing hypoxemia (low blood oxygen levels) and acute respiratory distress syndrome (ARDS) in influenza infections. The research aims to define the effects of PB1-F2 on alveolar type II (ATII)...
This Project Grant award of $451,000 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research conducted by The University of Texas Southwestern Medical Center (UT Southwestern) to develop a human lung alveolus-on-a-chip model for studying non-tuberculous mycobacteria (NTM) infections. The goal is to gain insights into NTM pathogenesis, host-pathogen interactions, and identify potential...
This $788,406 project grant from the National Institutes of Health National Institute of Allergy and Infectious Diseases, under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund the development of a sensitive, direct reading bioaerosol detection platform to quantify airborne pathogens such as SARS-CoV-2. Aerosol Devices Inc. will integrate their gentle condensation-growth capture sampler, which concentrates intact, viable virus particles into a small liquid volume...
This Project Grant award, totaling $744,977.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research at Emory University to explore the role of T cells in providing protection against respiratory virus transmission. Key objectives include defining the cellular interactions and molecular mechanisms of tissue-resident memory T cells (TRM) that can limit the spread of...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $143,450 to support research on developing therapies for treating viral-induced acute lung injury. The primary focus is on evaluating the therapeutic efficacy of combinations of PPARG agonist and RXR ligand compounds in cotton rat models of influenza and respiratory syncytial virus (RSV) infection. The research...
The University of Texas Health Science Center at Houston received a $568,909 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to conduct a 5-year research project titled "A Wastewater Approach to Viral Transmission, Evolution, and Ecology." The project aims to develop advanced computational models that integrate within-host viral kinetics and between-host transmission dynamics to improve...
This federal Project Grant award of $658,657, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research at the University of Virginia on the biophysical and functional coupling of protein condensates to ordered lipid domains in T-cells. The research aims to reveal the mechanisms by which protein condensates and membrane domains cooperatively regulate T-cell signal transduction and...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Vermont & State Agricultural College (UVM) in the amount of $438,983. The award, which runs from July 8, 2025 to June 30, 2027, will fund research to study the biological impact of a stable nucleocapsid (N) protein dimer formation in SARS-CoV-2. Specifically, the research aims to characterize viral growth...
This Project Grant award of $440,000 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research conducted by the University of Texas Medical Branch at Galveston (UTMB). The project aims to investigate the role of Rickettsia parkeri's cold shock protein A (CspA) as an exosome-specific RNA-binding protein that selectively enriches detrimental microRNAs (miR23a/27a/24/30b) in...
This Project Grant award, valued at $792,687.00 and issued by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to define the structural features of sialoglycans necessary for influenza A virus (IAV) infection and adaptation across various host species. The key activities under this award include: 1) using CRISPR/Cas9 techniques to truncate different types of sialoglycans in human lung...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $429,000 to the University of Texas at Dallas (UTD) to conduct research on the relationship between the chemical composition and viability of bioaerosols containing respiratory viruses like RSV. The 2-year project aims to: 1) determine the spatial distribution of chemicals and pathogens in bioaerosols using advanced microscopy techniques, and 2) study how the chemical composition of sub-5 micron and submicron bioaerosol particles impacts the decay rate of RSV viability. The research seeks to provide insights into airborne virus transmission dynamics, which can inform the development of improved ventilation and control measures.