This federal Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), focuses on evaluating the impact of gut microbiota composition on immune responses to malaria vaccines. The total award is $934,229 and began on June 24, 2024, with an expected completion date of April 30, 2026. The key objectives of the project are to: 1) Assess how differential gut microbiota populations in mice affect malaria vaccine-induced antibody responses, and 2) Investigate how gut microbiota communities from African and U.S. individuals shape malaria vaccine-induced antibody responses. The project involves collaboration between the primary awardee, Indiana University Indianapolis, and a sub-awardee, The Johns Hopkins University, which will be responsible for producing recombinant malaria vaccine antigens and mRNA complexes for use in the animal studies.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $194.7k | 3/14/25 | ||
| Not listed | $25.5k | 9/11/24 | ||
| Not listed | $25.5k | 9/11/24 | ||
| Not listed | $229.5k | 6/24/24 | ||
| Not listed | $229.5k | 6/24/24 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
10171S | The Johns Hopkins University | Project Grant R21AI186331 | $81.9k | 8/22/24 |