Project Grant R21AI182603
- This $147,656 federal Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand the role of transmembrane proteins in the cell division process of the malaria parasite Plasmodium falciparum. The award, effective January 22, 2025 through October 31, 2027, will enable the integration of biochemical and super-resolution microscopy approaches to decipher...
- This Project Grant award of $418,016 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research CFDA program supports research to explore the evolutionary origins of intracellular parasitism in apicomplexan organisms. The award aims to establish molecular and cellular mapping of the photosynthetic algae Chromera velia, which is closely related to apicomplexan parasites like those causing malaria and toxoplasmosis. Specifically, the...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $230,808 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University in St. Louis, Missouri. The funding will support research to identify heme-binding proteins in the malaria parasite Plasmodium falciparum and investigate their role in maintaining heme homeostasis. The project aims to better understand how the parasite detoxifies heme, an essential but redox-active...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $406,450 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Harvard T.H. Chan School of Public Health. The grant supports research to develop a continuous in vitro culture system for the Plasmodium vivax malaria parasite. Key objectives include optimizing the production of host reticulocytes (young red blood cells) to support P. vivax growth, iteratively improving culture conditions...
- This $501,800 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), to The Children's Hospital Corporation (doing business as Boston Children's Hospital) on August 4, 2025. The grant supports research to use cryo-electron tomography to gain new molecular insights into the divergent cell division process of the Plasmodium falciparum parasite, which causes malaria. The research...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $107,542 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University in Missouri. The grant, effective September 1, 2025 through August 31, 2027, aims to unravel the mechanisms underlying the differential sorting and trafficking of Plasmodium falciparum secreted proteins during the symptomatic stage of malaria. The research seeks to determine how exported proteins...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $375,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of South Florida (USF) to study the functions of messenger ribonucleoprotein (mRNP) granules in regulating mRNA metabolism in the malaria parasite Plasmodium falciparum. The project, running from Jun 10, 2025 to May 31, 2030, aims to identify mRNP markers, characterize their protein and mRNA compositions, and...
- The Project Grant award R01AI187153 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on identifying genetic factors associated with sexual stage development (gametocyte formation) in the malaria parasite Plasmodium falciparum. The $700,288 award, with a project period from Nov 2024 to Oct 2029, will fund a research project at the University of South Florida to perform...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $385,816 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Iowa State University of Science and Technology to conduct research on disrupting the DNA replication of the malaria parasite Plasmodium's apicoplast. The research aims to identify and characterize key proteases involved in processing the essential PREX protein needed for apicoplast DNA replication, in order to inform the...
- This federal Project Grant award of $791,864 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to identify molecular factors controlling chromatin organization and gene regulation in the malaria parasite Plasmodium falciparum. The research aims to elucidate the importance of long non-coding RNAs (lncRNAs) in parasite development, virulence, and sexual differentiation, with the goal...
This Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $426,250 to support research on understanding the function of the PEX4 and PEX22 proteins in Apicomplexan parasites, which cause diseases such as malaria and toxoplasmosis. The research team at Boston College aims to investigate how these peroxisome-derived proteins, which are essential for the pathogenic stages of the Apicomplexan life cycle, contribute to the secretory pathways and organelle biogenesis in these parasites. The project will run from August 1, 2025 to July 31, 2027 and could lead to insights that inform the development of new treatment strategies for Apicomplexan-caused diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $426.3k | 7/30/25 |