Project Grant R21AI180738

Award Date 8/26/24
Completion Date 6/30/26
Dollars Obligated $390K
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Moscow, ID 83844, USA
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This federal Project Grant award of $130,950 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research at the University of Idaho to understand the developmental cycle of Chlamydia bacteria at the single-cell level. The key objectives are to: 1) Develop a CRISPR-based knockdown screen to assess the role of essential genes in regulating Chlamydia cell type function and the developmental...
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This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $390,000 to the Regents of the University of Idaho to study the developmental cycle of Chlamydia bacteria at the single-cell level. The award supports two research aims: 1) developing a CRISPR interference screen to assess the role of essential genes in regulating Chlamydia cell types, and 2) determining the spatial gene expression patterns and DNA elements that generate cell-type specific gene expression in Chlamydia. The findings are expected to provide a more complete understanding of the Chlamydia developmental cycle and enable further investigation of the effects of mutations, chemical agents, and therapeutic treatments on the different cell forms. The award period runs from August 26, 2024 to June 30, 2026.

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