Project Grant R21AG102223
- Federal Grant Award Summary The University of Nebraska Medical Center received a $3.24 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) awarded September 15, 2025, with completion scheduled for September 14, 2029. This award funds a longitudinal research study examining how interpersonal connectedness between persons with Alzheimer's disease (AD) and their spousal caregivers influences early AD progression. The research employs a...
- Federal Grant Award Summary Funding Agency and Program: National Institute on Aging (NIA), Aging Research Program (CFDA 93.866) Award Details: $519,500 Project Grant awarded May 15, 2026, with completion date April 30, 2028 Products and Services Delivered: Vanderbilt University Medical Center will conduct a two-year research investigation examining epigenetic age acceleration (EAA) and its manifestation across immune cell populations in people living with and without HIV (PWH). The primary...
- Federal Grant Award Summary The University of Miami, through its Office of Research Administration within the School of Medicine, received a $109,652.00 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) effective September 5, 2026, with a one-year completion date of September 4, 2027. This award funds research investigating T cell senescence-driven immune dysfunction in aging and HIV-positive populations. The research aims to elucidate the mechanisms by...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Nebraska Medical Center (UNMC) a Project Grant totaling $544,256 under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate the role of microglial ferritinophagy in HIV and cocaine-mediated neuroinflammation. The research project, initiated May 15, 2026 and concluding February 28, 2031, addresses the persistent neuroinflammation and cognitive decline experienced by approximately...
- Federal Grant Award Summary Georgetown University received $788,121 in funding from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded August 1, 2025, to conduct a five-year multidisciplinary study investigating Alzheimer's disease and related dementias (ADRD) risk factors in Black/African Americans living with HIV. The study responds to the National Institute on Aging's directive to increase enrollment of underrepresented populations in ADRD research by examining...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Alabama at Birmingham $5,057,416 under the Aging Research program (CFDA 93.866) on September 15, 2025, for a four-year project extending through September 14, 2029. This Project Grant supports research examining the impact of undiagnosed Alzheimer's disease and related dementias (ADRD) on healthcare utilization across geographic regions in the United States. The research addresses a critical gap...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Texas Medical Branch at Galveston $1,112,821 under the Aging Research program (CFDA 93.866) for a five-year project period spanning January 1, 2026, through December 31, 2030. This Project Grant supports biomedical research investigating the interplay between microglia activation and tau oligomer polymorphs in cognitive resilience among Alzheimer's disease patients. The research focuses on...
- Federal Project Grant Award Summary The National Institute on Aging (part of the Aging Research program, CFDA 93.866) awarded a $397,416 Project Grant to the University of Massachusetts Medical School on September 4, 2025, with a completion date of May 31, 2027. Under the direction of Principal Investigator Dr. Zintis Inde, this award funds research investigating apoptotic dysregulation across cell types in aging and neurodegeneration, with specific focus on understanding how programmed cell...
- Federal Project Grant Award Summary The National Institute on Aging awarded the University of Rochester a Project Grant of $656,829 under the Aging Research program (CFDA 93.866), effective January 1, 2026, through December 31, 2030. This award funds research investigating the selective vulnerability of the fronto-insular network (FIN)—comprising the medial prefrontal cortex and anterior insular cortex—in aging and Alzheimer's disease (AD). The project integrates in vivo structural,...
- Federal Project Grant Award Summary The University of Nebraska Medical Center received a $644,298 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded February 1, 2026, with completion targeted for January 31, 2031. This award funds research to develop and validate next-generation regenerative cell-based therapies for peripheral artery disease (PAD), a progressive vascular condition characterized by arterial narrowing and blockage in the legs that...
The National Institute on Aging (NIA) awarded the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center (UNMC) division, a Project Grant totaling $422,125 under the Aging Research program (CFDA 93.866). The award, effective June 1, 2026, through May 31, 2028, funds research investigating the roles of misfolded protein aggregates on latent viral reservoirs in simian immunodeficiency virus (SIV)-infected, antiretroviral therapy (ART)-treated aged rhesus macaques. This research addresses a critical gap in understanding how age-associated amyloid fibril deposition and chronic inflammatory conditions may facilitate the reactivation and expansion of lymphoid and myeloid latent reservoirs in older people living with HIV. The project leverages the rhesus macaque model to comprehensively examine the intersection of HIV infection, chronological aging, and Alzheimer's disease-related dementias (AD-ADRD)—a particularly relevant investigation given that over half of all people living with HIV in the United States are aged 50 years or older. By conducting this research at UNMC in Omaha, Nebraska, the award supports biomedical research directed toward understanding mechanisms of aging and age-related diseases, consistent with NIA's mission to prevent and treat Alzheimer's disease and related dementias while advancing knowledge of HIV persistence despite effective antiretroviral therapy.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $422.1k | 5/19/26 |