Project Grant R21AG095387
- The National Institute of Environmental Health Sciences awarded The Research Foundation for the State University of New York $467,507 on August 1, 2026, to investigate occupational heat exposure and kidney function in restaurant workers under the Environmental Health program (CFDA 93.113). The recipient will partner with restaurants in the Southern U.S. to assess occupational heat exposure and kidney function across three-day periods in both cold and warm seasons, investigate worker knowledge of...
- The National Institute of Environmental Health Sciences awarded $444,125 to Duke University on April 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate molecular mechanisms linking inhaled silica exposure to kidney injury through lung-kidney organ crosstalk. The research addresses a critical knowledge gap in understanding how airborne silica contributes to remote kidney tubule injury and chronic kidney disease of unknown etiology, particularly in communities with...
- The National Institute of Environmental Health Sciences awarded the University of Miami $2,269,361 on September 15, 2025, under the Environmental Health program (CFDA 93.113) to investigate urban heat island exposure and its impact on Alzheimer's disease and related dementia outcomes among older adults in South Florida. The study will measure recent and cumulative urban heat island exposure for 500 participants in the Healthy Brain Initiative, a longitudinal cohort of 50-year-olds with no,...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $1,589,358 to Trustees of Indiana University on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct research identifying the contribution of work-related heat stress and hyperthermia exposure to subclinical acute kidney injury and chronic kidney disease of nontraditional causes in outdoor workers. The research addresses occupational kidney disease...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Alabama at Birmingham $650,509 on August 20, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the myeloid ferritin–CXCL3 axis as a driver of acute kidney injury (AKI) progression to chronic kidney disease. The research leverages novel transgenic mice with targeted deletion of ferritin genes in myeloid cells to determine whether myeloid...
- The National Institute of Environmental Health Sciences awarded the University of North Carolina at Chapel Hill $207,384 on September 14, 2025, under the Environmental Health program (CFDA 93.113) to examine how gestational exposure to extreme heat and neighborhood heat vulnerability affect blood pressure trajectories during early childhood. The research addresses gaps in the literature on the relationship between heat stress exposure and cardiovascular health in children. The study will...
- The National Institute of Environmental Health Sciences (NIEHS), part of the Department of Health and Human Services National Institutes of Health, awarded $423,500 to Texas A&M University System Health Science Center on May 22, 2026, under the Environmental Health Program (CFDA 93.113, Assistance Listing designation R21ES038666). The recipient will investigate the effects of temperature-sensitive ion channels in platelets and how increases in core-body temperature modulate platelet-mediated...
- The National Institute of Environmental Health Sciences, part of the Department of Health and Human Services National Institutes of Health, awarded $471,196 to Aurora Health Care, Inc. on September 1, 2026, under the Environmental Health program (CFDA 93.113) to examine how weather-related barriers affect primary care utilization in older adults with chronic conditions. The recipient will quantify the impact of inclement weather—including extreme temperatures, high heat index, and heavy...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Alabama at Birmingham $173,232 on May 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds basic research into renal endothelial cell signaling in sepsis-associated acute kidney injury (SA-AKI) preceded by viral priming. The research examines how renal endothelial cells respond to poly(I:C), a synthetic analog of viral double-stranded...
- Federal Grant Award Summary The University of Maryland, College Park received a $417,272 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded on September 20, 2025, with a completion date of September 19, 2027. This research initiative will develop the first early-warning system designed to enhance the resilience of dialysis communities against health threats from wildfires and extreme heat events (EHEs)....
The National Institute of Environmental Health Sciences awarded the University of Alabama at Birmingham $409,750 on August 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate the mechanisms by which recurrent heat stress-induced dehydration injures kidney function in aging and aged mice. The research will test whether repeat heat stress accelerates age-related kidney functional decline, whether it exacerbates pro-inflammatory versus anti-inflammatory immune cell ratios in aged kidneys, and whether specific macrophages or T cells drive heat stress-induced kidney injury. The studies will employ male and female mice at ages spanning young adulthood (26 weeks) through advanced age (78 weeks) and model chronic high-temperature exposure experienced by outdoor workers. The award runs from August 1, 2026, through July 31, 2028, with performance at the University of Alabama at Birmingham in Birmingham, Alabama. The work addresses epidemiological findings linking high heat exposure to increased chronic kidney disease incidence and the particular vulnerability of individuals over age 60 to heat stress, while also examining age-related physiologic changes including nephron loss and immune system dysregulation that may predispose older individuals to dehydration-related kidney complications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $409.8k | 7/29/26 |