Project Grant R21AG093259
Award Date
5/1/25
Completion Date
4/30/27
Dollars Obligated
$424K
Federal Agency
National Institute on Aging
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
California, USA
Similar Awards
This $153,056 federal Project Grant award, provided by the National Institute on Aging under the Aging Research program (CFDA 93.866), supports research on the neurocognitive mechanisms underlying age-related declines in episodic memory representational specificity. The project aims to: (1) identify EEG correlates of variations in episodic memory specificity among young and older adults, (2) use computational modeling to understand the cognitive processes accounting for these variations, and (3)...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to Duke University provides $2,306,767 in funding to study the neural mechanisms underlying attentional resilience in older adults. The central objective is to understand how robust attentional control processes, such as the ability to modulate brain alpha power and enhance sensory processing, enable individuals to maintain cognitive function despite physiological stressors like neuroinflammation or...
This federal Project Grant award, with ID R21AG091327, was provided by the National Institute on Aging under its Aging Research program (CFDA 93.866). The $442,938 grant supports research aimed at elucidating the changes in sleep, memory, and synaptic plasticity that occur with aging, with the goal of identifying mechanisms to prevent or reverse age-related memory decline. The primary research activities include: 1) characterizing post-training sleep and synaptic plasticity changes during memory...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $242,310 to the University of Florida to conduct a research study examining the relationship between cognitive load, anterior cingulate cortex (ACC) activity, and the coupling of the striatal and hippocampal brain networks during age-related cognitive decline. The goal is to better understand the neural mechanisms behind the shift from hippocampus-dependent to striatum-dependent learning...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $131,027 to The Leland Stanford Junior University to study neuronal proteostasis, or the maintenance of protein health, in the context of brain aging and Alzheimer's disease (AD). The research aims to understand how neuronal protein turnover is altered during aging and AD, the consequences of these changes for neuronal health, and the roles of the lysosome and microglia in regulating...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to The Leland Stanford Junior University (Stanford University) in the amount of $121,550 will support research to examine the effects of federal, state, and local governmental investments in early life on midlife cognition and later-life risk of Alzheimer's disease and related dementias (AD/ADRD). The research aims to (1) assess if county-level investments in legal systems or K-12 education during...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to The Leland Stanford Junior University will support research into using afternoon phototherapy to address sleep-wake fragmentation and slow cognitive decline in older adults with mild cognitive impairment (MCI). The $131,085 award will fund a 2-year research study that leverages state-of-the-art machine learning techniques to identify factors contributing to sleep-wake fragmentation and cognitive...
The National Institute on Aging (NIA) awarded a $148,568 Project Grant under CFDA 93.866 - Aging Research to Brandeis University to conduct research on the neurobiological mechanisms underlying daily life activity participation in older adults and its relationship to Alzheimer's disease pathology. The project will employ a multilevel, multimodal approach combining behavioral, psychophysiological, neuroimaging, and naturalistic methods to examine the impact of age-related motivational shifts on...
This National Institutes of Health (NIH) National Institute on Aging federal Project Grant Award (CFDA 93.866) aims to develop a new conceptual and operational framework for quantifying biopsychological mismatch during cognitive training in older adults with mild cognitive impairment (MCI). The $125,847 award to The Leland Stanford Junior University will support research to: 1) Analyze an existing dataset on speed of processing training to examine how biopsychological mismatch, measured...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) totaling $1,548,995 supports research to elucidate the cognitive and neural mechanisms underlying the benefits of environmental support on associative memory in younger and older adults. The primary awardee, The Pennsylvania State University, will leverage high-resolution fMRI to investigate how schematic and perceptual grouping principles can enhance associative memory by creating unitized...