Project Grant R21AG091823
- The University of Texas Health Science Center at Houston (UTHealth) received a $1,238,672 federal Project Grant award from the National Institute on Aging under the Aging Research program (CFDA 93.866) with an award date of September 1, 2023. The grant supports research to examine the pathological role of von Willebrand factor (VWF) within the wall of leptomeningeal arteries and arterioles, and its potential to impair cerebrovascular function and vascular-mediated clearance of amyloid-beta...
- The National Institute on Aging, part of the Department of Health and Human Services' National Institutes of Health, awarded $3,724,674 under the Aging Research program (CFDA 93.866) to Texas Tech University Health Sciences Center in Lubbock, Texas. The three-year project grant beginning September 15, 2022 will support research into the impacts of microrna-455-3p (miR-455-3p) in Alzheimer's disease. Specifically, the grantee will investigate the neuroprotective effects of overexpressing and...
- The National Institute on Aging (NIA), part of the Department of Health and Human Services National Institutes of Health, awarded a $3.37 million Project Grant to The University of Texas at Arlington to develop an individualized deep connectome framework for Alzheimer's disease and related dementias (ADRD) analysis. The three-year grant, awarded on August 18, 2022 under the NIA's Aging Research program (CFDA 93.866), will support research to discover and identify individualized...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $372,904 to The University of Texas Health Science Center at San Antonio to advance cross-national research on aging and cognitive function. The 5-year grant, awarded on September 20, 2025, supports an annual program that recruits, trains, and mentors 16 post-graduate participants dedicated to mastering Down syndrome (DS) clinical research. The program offers hands-on DS clinical...
- The University of Texas at Austin was awarded a $438,625 Project Grant from the National Institute on Aging (CFDA 93.866 Aging Research program) to conduct research on "DECODING THE HETEROGENEITY OF INTERNEURON VULNERABILITY IN AGING AND ALZHEIMER'S DISEASE: AN ULTRAPLEX CLEM APPROACH." The project aims to better understand how different subtypes of inhibitory interneurons in the hippocampus are impacted by aging and Alzheimer's disease, and how some interneurons may be more...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to investigate how aging produces ultrastructural alterations to neuronal autophagy, which is critical for maintaining neuronal homeostasis and function. The $429,000 award to the University of Texas Health Science Center at Houston will be used to accomplish two specific aims over the 2-year project period starting January 1, 2025: Compare the ultrastructural features of axonal autophagic...
- The National Institute on Aging (NIA), through its Aging Research federal grant program (CFDA 93.866), awarded a $636,342 Project Grant to Trustees of Boston University (doing business as Boston University Medical Campus) to conduct research on normal and pathological brain aging. The grant, with a performance period from August 1, 2025 to April 30, 2030, will support a multiscale modeling and empirical study of progressive myelin dystrophy, loss of synapses, and neuronal hyperexcitability in...
- The National Institute on Aging (NIA) awarded a $205,000 project grant to The University of Texas Southwestern Medical Center (UT Southwestern) under the Aging Research federal grant program (CFDA 93.866) to implement an innovative optical MRI (OMRI) technique for time-resolved visualization of clock gene expression patterns in living mouse brains. The project aims to leverage the strengths of bioluminescent imaging and MRI to precisely track rhythmic gene expression, with a focus on the PER2...
- The National Institute on Aging awarded $3,391,684 under the Aging Research grant program (CFDA 93.866) to Texas A&M University Health Science Center from May 1, 2022 to April 30, 2025. The project aims to test the hypothesis that peripheral insulin-like growth factor-1 (IGF-1), delivered intraperitoneally or orally, will improve acute stroke disability as well as chronic depressive-like behaviors and cognitive impairment post-stroke in a rodent model. Researchers also expect peripheral...
- This Project Grant award of $429,000 was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to the University of Texas Health Science Center at Houston to investigate the role of metal regulatory transcription factor-1 (MTF-1) in neurodegeneration and dementias. The research aims to determine if aberrant activation of MTF-1 is necessary and sufficient for driving neurodegeneration in fly models of Alzheimer's disease, tauopathies, and Lewy body dementia. It will also...
The University of Texas Health Science Center at Houston (UTHealth) was awarded a $417,800 Project Grant from the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) to conduct research on "Senescence Induced by Iron Overload in the Brain Vasculature". The grant award period runs from September 15, 2025 to August 31, 2027. The Aging Research program supports comprehensive scientific investigations focused on understanding the biological, clinical, and social aspects of aging, with a particular emphasis on Alzheimer's disease and related dementias. Through this grant, UTHealth will perform research to advance scientific knowledge about the aging process and develop innovative solutions to address critical health challenges for the aging population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $417.8k | 9/15/25 |