Project Grant R21AG091161
- This $4,765,698 federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) will fund a research study by the University of California, Santa Barbara to investigate the effects of endocrine aging on spatial navigation ability and its neuronal systems. The project will enroll 240 cognitively normal midlife adults, with a balanced distribution of pre-, peri-, and post-menopausal women, and use immersive virtual environments and brain imaging to elucidate how...
- This federal Project Grant award of $145,566 from the National Institute on Aging (CFDA 93.866 - Aging Research) is supporting research at the Icahn School of Medicine at Mount Sinai to investigate how the brain accumulates and utilizes "cognitive maps" - internal neural representations that enable flexible behavior and memory recall. The research aims to provide insights into the neuronal coding deficits underlying cognitive decline, with the goal of informing therapeutic...
- The National Institute on Aging (NIA) awarded a $713,723.32 Project Grant under the Aging Research Federal Grant Program (CFDA 93.866) to the Albert Einstein College of Medicine in Bronx, NY. The award, effective from February 1, 2025 to January 31, 2028, will support research on the influence of neighborhood characteristics, both objective and subjective, as well as GPS-based personal activity space measures, on cognitive decline, Alzheimer's disease and related dementias (ADRD), and...
- This Project Grant award from the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) aims to develop, evaluate, and implement virtual reality (VR)-based cognitive stimulation games to enhance attention and prevent delirium in older surgical patients with cognitive impairment. The $242,840 award, effective September 2, 2025, will support a 5-year randomized controlled pilot trial led by Dr. Hina Faisal, an Assistant Professor at the Houston Methodist...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $705,385 to Northeastern University to conduct a large-scale study investigating mediators and moderators of executive function training in older adults. The study aims to improve the rigor and reproducibility of research on cognitive plasticity in older adults, many of whom are at risk for Alzheimer's disease and related dementias. The study will collect data from 1,250 older adults aged 60+ to...
- The National Institute on Aging (NIA), part of the Department of Health and Human Services, awarded a $120,858 project grant under the Aging Research federal grant program (CFDA 93.866) to the University of Maryland, Baltimore. The grant will fund the "Preserving Ability through Virtual Exercise (PAVE)" project, which aims to explore the feasibility and preliminary efficacy of a virtual reality physical activity intervention to help older adults maintain physical function during...
- This federal Project Grant award, funded by the National Institute on Aging (CFDA 93.866 - Aging Research program), provides $1,353,901 to Rendever, Inc. to develop and test a virtual reality (VR) platform that aims to improve mental health and social connectivity for older adults, particularly those living at home and at risk of social isolation. The award, granted on September 22, 2025, will support Rendever's efforts to expand the availability of its clinically-validated VR technology...
- This Project Grant award, titled "Investigating Neurosciences, A Summer Program to Ignite Research and Education (INSPIRE)", is funded by the National Institute on Aging (CFDA 93.866 - Aging Research) with $215,998.00 and will be implemented from September 2025 to May 2030. The goal of this program is to create an immersive research education initiative that will attract undergraduate science majors to ultimately increase the number of early-stage investigators pursuing careers in...
- This federal Project Grant award of $461,146 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Yale University supports research toward developing a navigation model of the aging brain in the marmoset. The key objectives are to: Determine if the functional organization of the marmoset entorhinal cortex (ERC) is similar to rodents and macaques, as the ERC is an initial site of cortical tau pathology and degeneration in Alzheimer's disease. Examine the relationship between...
- This federal Project Grant award of $307,000.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to conduct a single, highly powered study to identify memory processes that are most sensitive to the asymptomatic, preclinical stage of Alzheimer's disease (AD) pathology. The study combines a continuous report item-location associative memory task with advanced behavioral and neural modeling to estimate subtle changes in memory precision that may differentiate healthy...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $220,132 to Albert Einstein College of Medicine to design a spatial navigation intervention protocol informed by region-specific brain activation for individuals at risk for dementia. The project aims to 1) determine the feasibility of a virtual reality-based spatial navigation training protocol, and 2) explore training-induced neuroplasticity in older adults participating in the virtual reality exercises. The award period runs from Aug 15, 2025 to Jul 31, 2027. This pilot project is focused on addressing spatial navigation difficulties, which are an early sign of Alzheimer's disease, by leveraging immersive virtual reality technology and mobile brain-body imaging to better understand brain activity during active spatial navigation.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $220.1k | 8/8/25 |