Project Grant R21AG085881

Award Date 9/30/24
Completion Date 8/31/26
Dollars Obligated $850K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Florida, USA
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This $825,135 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research at the Massachusetts General Hospital to investigate the relationships between gut microbiome-related metabolites, cerebrovascular disease, Alzheimer's disease biomarkers, and cognitive impairment. The research will leverage data from the REGARDS and CARDIA longitudinal cohort studies to examine associations between gut microbiome metabolites, brain imaging markers, and the...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the University of Massachusetts Medical School is focused on understanding how the gut microbiome influences neurodegeneration and protects against Alzheimer's disease. The $647,979 award, effective September 30, 2024 through August 31, 2025, will leverage the C. elegans model system to: Determine how bacterial production of vitamin B12 protects against neurodegeneration pathways. Examine...
The University of South Florida received a $3,385,215 Project Grant award from the National Institute on Aging, part of the National Institutes of Health within the Department of Health and Human Services. The grant was awarded under the Aging Research program (CFDA 93.866) to fund research titled "Microbial Therapy Improves Gut Permeability to Reduce Cognitive Decline and Alzheimer's Disease." The grant will support research from August 2021 through July 2024 to study the impact of...
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This Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) provides $310,000 in funding to Wake Forest University Health Sciences to identify microRNA (miRNA) biomarkers and regulatory targets associated with early cognitive impairment and progression to Alzheimer's disease (AD). The key objectives are to: 1) Identify circulating miRNA biomarkers that can discriminate between individuals at distinct stages of AD progression, including early...
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