Project Grant R21AA031170
- This federal Project Grant award of $396,643 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) supports research to elucidate the mechanisms underlying stress-potentiated ethanol drinking. The project aims to investigate the role of the histone methyltransferase G9a and its effects on dynorphin-positive neurons in the nucleus accumbens to regulate this behavior. Key objectives include testing the hypothesis that G9a's effects on...
- This federal Project Grant award of $2,150,570 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) to Brown University. The funding supports research to investigate the circuit and molecular mechanisms through which alcohol influences natural reward systems in the brain. Specifically, the project aims to use the reduced numerical complexity of the Drosophila (fruit fly) reward/dopaminergic system as a model to study...
- This federal Project Grant award for $700,000.00, issued by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program, supports research to investigate the neurophysiological and genetic factors contributing to binge drinking and alcohol use disorder. The primary awardee, the University of New Mexico (UNM) Health Sciences Center, will leverage techniques such as monosynaptic circuit labeling, optogenetics, electrophysiology,...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $1,742,166 Project Grant under CFDA 93.273 - Alcohol Research Programs to the Trustees of Boston University, doing business as Boston University Medical Campus. The grant supports a comprehensive evaluation to assess the associations of state alcohol taxation and related policy environment with state-level alcohol treatment facilities capacity and key alcohol use disorder (AUD) health service outcomes. The project...
- This federal Project Grant award of $2,552,568.00, awarded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) program, supports research to investigate the relationship between stress-induced neuroadaptations in the insula-BNST pathway and subsequent alcohol use disorder (AUD)-related behavior. The project, conducted by Wake Forest University Health Sciences, aims to elucidate how stress activation of AUD-associated...
- This federal Project Grant award of $337,500.00, awarded on September 5, 2025 by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), supports a research project titled "Kappa Opioid Receptor Modulation of BLA Inputs to the BNST and Stress-Escalated Drinking" under the NIAAA's Alcohol Research Programs (CFDA 93.273). The project aims to investigate the neural mechanisms by which social stress leads to increased alcohol consumption, with a focus on the role of the kappa...
- This $156,204 Project Grant was awarded on May 15, 2025 by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) to the University of Massachusetts Medical School (UMMS) in Worcester, MA. The grant funding supports research on the role of protein kinase C delta (PKCδ)-expressing neurons in the bed nucleus of the stria terminalis (BNST) in compulsive ethanol intake behaviors. The research aims to utilize an operant conditioning task...
- This federal Project Grant award, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports research to investigate the effects of chronic intermittent alcohol exposure on orbitofrontal cortex (OFC) astrocyte physiology, structure, and gene expression, and how these changes contribute to altered OFC neuron excitability and excessive drinking behaviors. The $459,707 award, with a period of performance from September 5,...
- This Project Grant award was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), which falls under the federal Alcohol Research Programs (CFDA 93.273). The $692,723 award will support a double-blind, placebo-controlled clinical trial to test whether the drug suvorexant can be used as a novel therapeutic for alcohol use disorder (AUD) and stress-related drinking. The 5-year project, running from September 2025 through August 2030, will be conducted by researchers at The...
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) provides $431,918 in funding to Bryant University for a research project focused on understanding the neural circuitry mechanisms underlying maladaptive reward memories related to alcohol addiction. The research aims to use the genetic tractability of the Drosophila melanogaster model organism to investigate how alcohol disrupts memory circuit activity and drives...
This federal Project Grant award, funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), will support research on the role of somatostatin in the central amygdala in relation to heavy alcohol drinking. The research team at Boston University Medical Campus will use an animal model of heavy alcohol drinking, combined with pharmacological, molecular, and electrophysiological approaches, to test the hypothesis that activation of the somatostatin/somatostatin receptor 2 system in the central amygdala can act as a brake on heavy alcohol drinking by buffering stress systems. The $221,401 award will fund this research project over a 2-year period from September 1, 2025 to August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 8/28/25 | ||
| Not listed | $221.4k | 8/22/25 |