This federal Project Grant award, provided by the Agency for Healthcare Research and Quality (AHRQ) under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program, aims to implement and evaluate strategies to increase the use of oral antibiotics for children hospitalized with pneumonia. The $148,882 award will fund a pilot hybrid trial led by Dr. Jillian Cotter at the University of Colorado-Denver to: 1) identify barriers and facilitators to increasing initial oral antibiotic...
This Project Grant award, valued at $999,998.00 and funded by the Agency for Healthcare Research and Quality (AHRQ) under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program, aims to evaluate the implementation of antibiotic stewardship (AS) strategies and equity standards in urgent care clinics and federally qualified health centers (FQHCs) in the Chicagoland area. The study will assess disparities in antibiotic prescribing and the factors driving these inequities,...
The U.S. Department of Health and Human Services, Agency for Healthcare Research and Quality (AHRQ) awarded a $153,050 Project Grant under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program to The Children's Hospital Corporation (doing business as Boston Children's Hospital). The grant, with a period of performance from July 1, 2024 to June 30, 2029, will fund the development and implementation of a machine learning prediction model to identify children at high risk for...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will provide $197,748 to conduct research on healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) in neonatal intensive care units (NICUs). The key objectives of this research project are to: 1) Identify nosocomial transmission of viral and bacterial pathogens in the NICU through metagenomic...
This Project Grant award from the Agency for Healthcare Research and Quality (AHRQ) under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program provides $275,000 to the University of Texas Health Science Center at Houston over a 2-year period from August 1, 2024 to July 31, 2026. The funded project aims to develop and test strategies to increase implementation of evidence-based interventions by patient advocacy groups in three areas: juvenile idiopathic arthritis, multiple...
This $714,638 Project Grant awarded by the National Institute of Child Health and Human Development (CFDA 93.865) will fund a hybrid effectiveness-implementation trial of the CAARE (Caregivers' Aid to Accelerate Recovery after Pediatric Emergencies) intervention. CAARE is a technology-assisted, stepped-care intervention that provides emotional and behavioral screening, education, risk reduction, symptom self-monitoring, and referrals to evidence-based treatment for children under 12 and their...
The Research Institute at Nationwide Children's Hospital will receive $8.5 million over four years from the Defense Health Agency under the Military Medical Research and Development program to compare the long-term efficacy of tissue-engineered vascular grafts versus polytetrafluoroethylene conduits using an established preclinical model. The award, issued on September 30, 2022, will support research to transform military and public health care through innovative medical solutions for...
This federal Project Grant award, titled "BEDSIDE NOTES: A MULTICENTER TRIAL TO IMPROVE FAMILY CLINICAL NOTE ACCESS AND OUTCOMES FOR HOSPITALIZED CHILDREN," is funded by the Agency for Healthcare Research and Quality (AHRQ) under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program. The $800,000 grant aims to evaluate the impact of the "Bedside Notes" health IT intervention, which provides parents of hospitalized children real-time access to their...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), is providing $781,129 to The Regents of the University of California, San Francisco (UCSF) to conduct a prospective, multicenter cohort study of 400 critically ill children with acute respiratory failure. The key objectives are to: 1) independently validate the performance of UCSF's existing integrated host/microbe...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $455,000.00 to the Children's Research Institute to develop new therapeutic protocols for reducing sepsis mortality in pediatric populations. The key products and services to be delivered include: An AI-guided early identification tool for rapid sepsis detection, 2) Sepsis phenotyping and digital twin patient modeling to...