Project Grant R16GM166494
- The National Institute of General Medical Sciences awarded The University Corporation $405,625 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to discover and characterize thermoregulatory RNA elements in bacteria, phages, chloroplasts, and mitochondria. The funded work expands discovery and characterization of thermoregulatory RNAs—structured RNA elements that respond to heat stress—across prokaryotic and organellar genomes over five years. A major...
- The National Institute of General Medical Sciences awarded Southern Methodist University $399,927 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the molecular mechanisms of desiccation tolerance in anhydrobiotic organisms. The research deciphers how certain animals survive near-complete absence of water by identifying and characterizing protective molecules—specifically late embryogenesis abundant (LEA) proteins and small heat shock...
- The National Institute of Allergy and Infectious Diseases awarded The University Corporation $147,500 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a multi-scale study of antimicrobial peptide action in non-standard bacterial growth states. The project addresses how antimicrobial peptides (AMPs)—immune-derived molecules that kill bacteria by disrupting membranes and modulate host immune responses—perform under physiologically relevant...
- This three-year, $162,238 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research between Yale University, Stony Brook University, and researchers at examining and developing biomimetic peptides that inhibit ice formation. The researchers aim to understand and mimic antifreeze proteins in nature to generate synthetic antifreeze molecules for applications such as biological material preservation, food processing...
- The National Institute of General Medical Sciences awarded the University of California, Los Angeles $420,981 on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop engineered enzymatic catalysts for asymmetric hydrogen atom transfer reactions in synthetic chemistry. The research integrates organic chemistry, protein engineering, bioinorganic chemistry, and computational modeling to design and evolve biocatalysts that enable...
- The National Science Foundation Division of Biological Infrastructure awarded the Los Angeles County Museum of Natural History Foundation $932,855 on September 15, 2026, to upgrade cryogenic storage for the museum's zoological collections. The award funds acquisition of liquid nitrogen freezers operating at −196° Celsius and development of new sample management approaches for the Natural History Museum of Los Angeles County's animal tissue specimens. The museum holds one of the country's largest...
- The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded the University of Louisiana at Monroe $379,887 on August 15, 2026, under the Engineering program (CFDA 47.041) to conduct fundamental research on freeze-induced protein instability in cryopreservation. The project experimentally controls and quantifies air bubble formation during the freezing of water-based solutions and studies the impact of reducing bubble formation on protein...
- The National Institute of General Medical Sciences awarded the California State University Long Beach Research Foundation $146,819 on August 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop synthetic approaches for preparing arylated bioactive dihydrobenzofurans that modulate immune response. The project synthesizes five natural products—maceneolignan A, maceneolignan B, licarin A, licarin B, and acuminatin—and their structural analogs through...
- The National Institute of General Medical Sciences awarded the University Enterprises Corporation at California State University, San Bernardino $183,750 on August 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to fund research on the mechanisms of long-chain fatty acid transport through the FADL protein in Escherichia coli. The research addresses knowledge gaps in how the FADL transporter, an outer membrane protein in gram-negative bacteria, recognizes and...
- The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded CAL State La University Auxiliary Services Inc. $199,868 on May 1, 2026, for a project grant developing a multimodal embedding framework to accelerate antimicrobial peptide discovery using artificial intelligence. The project addresses antibiotic resistance by designing antimicrobial peptides (AMPs) as alternatives to traditional antibiotics through advanced AI techniques. The...
The National Institute of General Medical Sciences awarded CAL State LA University Auxiliary Services Inc. $150,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop robust and highly efficient bio-antifreezes for long-term biopreservation. The project runs through March 31, 2030, with performance in Los Angeles, California. The research systematically determines the stability of key components within bio-antifreeze systems—specifically insect antifreeze proteins paired with small molecule enhancers—and pairs those analyses with quantitative assessment of functional activity. The work addresses a critical gap in understanding how antifreeze protein stability regulates enhancing activity in bio-antifreeze systems and their overall effectiveness. Success will provide mechanistic insights to guide rational development of cryoprotectant agents less toxic and more effective than current alternatives for long-term storage of cells and biological materials.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $150.0k | 7/21/26 |