Project Grant R16AI201108
- The National Institute of Allergy and Infectious Diseases awarded Kansas State University $738,183 on July 20, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to characterize the immunoregulatory protease network that controls melanization in Anopheles gambiae, the African malaria mosquito vector. The research identifies molecular interactions that regulate phenoloxidase activation and melanization cascade proteases, with the objective of understanding how protease...
- The National Institute of Allergy and Infectious Diseases, operating under the Department of Health and Human Services, awarded Kansas State University $238,247 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on larval immunity in the African malaria mosquito Anopheles gambiae. The project identifies molecular interactions that regulate melanization through proteolytic activation of phenoloxidase in An. gambiae larvae, with the...
- The National Institute of Allergy and Infectious Diseases awarded the University of California, San Diego $480,000 on September 16, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the molecular basis for arboviral fitness in vector and reservoir hosts. The research examines how arboviruses replicate across evolutionarily distant hosts—insects and vertebrates—despite showing high specificity in their transmission cycles. Using alphaviruses as a...
- The National Institute of Allergy and Infectious Diseases awarded Iowa State University $578,956 on July 13, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support research on the regulation of axoneme assembly during Plasmodium falciparum gametogenesis, a study aimed at advancing malaria vaccine development. The project, designated R01AI195769, runs through June 30, 2031, with work performed in Ames, Iowa. The research addresses the mechanisms of flagellar...
- The National Institute of Allergy and Infectious Diseases awarded Texas State University $188,124 on August 17, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support research on the molecular basis for Plasmodium rhoptry development. The research investigates how the aspartic protease plasmepsin IX and the glycosylphosphatidylinositol-anchored rhoptry-associated membrane antigen coordinate during rhoptry maturation in the malaria parasite. Rhoptries are...
- The National Institute of Allergy and Infectious Diseases awarded Colorado State University $192,500 on August 19, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the role of enteroendocrine cells in West Nile Virus replication and transmission in Culex tarsalis mosquitoes. The research comprises two aims: Aim 1 will use dissociated midgut cells from colonized mosquitoes infected with barcoded WNV, flow cytometry, and sequencing to quantify the...
- The National Institute of Allergy and Infectious Diseases awarded Duke University $273,337 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the role of persistent sodium currents in modulating mosquito sensory behavior and spatial repellency to transfluthrin, a volatile pyrethroid insecticide. The research focuses on understanding how transfluthrin-based spatial emanators—recommended by the World Health Organization for malaria...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $2.54M to the University of Texas Medical Branch at Galveston under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 8, 2025, for a four-year project period concluding August 31, 2029. This Project Grant supports investigator-initiated biomedical research examining the relationship between desiccation tolerance in Aedes aegypti mosquitoes and their...
- The National Institute of Allergy and Infectious Diseases awarded Whitehead Institute for Biomedical Research $899,850 on February 20, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate how apicomplexan parasites recognize and invade host cells. The funded research examines the molecular mechanisms by which parasites such as Toxoplasma and Plasmodium trigger rhoptry discharge—the secretion of proteins from specialized organelles upon contact with host...
- The National Institute of Allergy and Infectious Diseases awarded Duke University $148,614 on March 23, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support interdisciplinary training and research experience in vector-borne disease epidemiology, migration, and environmental health. The award funds a fellowship supporting mentored training in the assessment of malaria transmission dynamics near migrant communities in Panama's Darien and Guna Yala regions....
The National Institute of Allergy and Infectious Diseases awarded New Mexico State University $146,671 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 3, 2026, for a project grant (R16AI201108) investigating the link between immunometabolism and epigenetics in the malaria vector mosquito Anopheles stephensi. The project employs a multi-omics approach integrating metabolomic, epigenomic, and transcriptomic data to establish mechanistic linkages between immunometabolism and epigenetic regulation in anti-parasitic immunity within the vector. The research focuses on lactate-mediated histone lactylation as a potential epigenetic mechanism governing mosquito immune response to malaria parasites, using ATAC-seq, CUT & TAG, and RNA-seq methodologies. The project will serve as a training platform for graduate and undergraduate students in cutting-edge multi-omics research approaches. Work is performed in New Mexico, USA, with a period of performance extending from September 3, 2026, through August 31, 2030. The assistance type is a project grant. This award falls under the National Institutes of Health's broader Allergy and Infectious Diseases Research program, which supports biomedical research and research training in infectious diseases and related areas at public and private nonprofit institutions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $146.7k | 9/3/26 |