Project Grant R15NS147330
- The National Institute of Neurological Disorders and Stroke awarded the New Jersey Institute of Technology $426,456 on May 6, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop treatment of neonatal hypoxic-ischemic encephalopathy using echogenic noble gas microbubbles. The project addresses a clinical gap: hypoxic-ischemic encephalopathy causes significant mortality and long-term neurological disability in children,...
- The National Institute of Neurological Disorders and Stroke awarded Rutgers The State University of New Jersey, doing business as RBHS-School of Nursing, $1.84 million on September 5, 2026, to investigate phosphodiesterase 2A signaling in traumatic brain injury and Alzheimer's disease under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The project examines how phosphodiesterase 2A modulates voltage-dependent anion channel 1...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The University of Kentucky Research Foundation $192,500 on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate chronic neurovascular dysfunction following repetitive mild traumatic brain injury. The funded research examines how repetitive mild blast TBI...
- The Defense Health Agency awarded a $1,369,230 Project Grant to the New Jersey Institute of Technology (NJIT) under the Military Medical Research and Development program (CFDA 12.420). The grant, effective September 15, 2024, supports a 3-year research project titled "A Transcutaneous Electrode-Induced Valsalva-Like Maneuver for the Prevention of Blast Induced Pathophysiology and Behavioral Deficits in the Ferret." The research aims to develop a novel technique using transcutaneous...
- The National Institute of Neurological Disorders and Stroke awarded New Jersey Institute of Technology $558,167 on July 25, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop an AI-driven robotic transcranial magnetic stimulation (TMS) system for high-resolution cortical mapping. The project addresses spatial inaccuracy in conventional manual TMS systems, which typically introduce positioning errors exceeding 5–11...
- This $6,214,900 Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program supports research on the role of genetic risk factors and immune response on neurovascular unit (NVU) function in post-traumatic brain injury (TBI) cognitive impairment. The primary awardee, the Scintillon Institute, a non-profit biomedical research organization in San Diego, California, will conduct this advanced scientific investigation over...
- The National Institute of Neurological Disorders and Stroke awarded Worcester Polytechnic Institute $554,927 on June 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and validate a reproducible blast-related traumatic brain injury model in the nematode C. elegans that enables controlled exposure to blast pressure waveforms with real-time measurement of neuronal activity and behavior in vivo. The research addresses...
- The National Institute of Neurological Disorders and Stroke awarded The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. $372,880 on July 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating lateral habenula circuit dysfunction in mild traumatic brain injury and its causal contribution to associated neuropsychiatric disorders including depression, anxiety, and...
- The National Institute of Neurological Disorders and Stroke awarded New Jersey Institute of Technology $553,292 on March 11, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to engineer an in vitro three-dimensional tissue construct for studying peripheral nerve regeneration. The recipient will develop 3D hollow channel systems seeded with embryonic dorsal root ganglia explants and coated with specific extracellular matrix...
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded $232,605 to the University of Pennsylvania on July 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), a Project Grant assistance type. The recipient will isolate and characterize microglial-derived extracellular vesicles as biomarkers for traumatic brain injury. The...
The National Institute of Neurological Disorders and Stroke awarded New Jersey Institute of Technology $559,641 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). NJIT is developing ultrasound-activated therapeutic gas microbubbles for treatment of mild traumatic brain injury induced by repetitive low-level blasts. The research targets military, law enforcement, veterans, and civilian personnel exposed repeatedly to blast injuries through routine training or field exposure, who often develop chronic conditions including post-traumatic stress disorder, depression, anxiety, and memory loss. The work hypothesizes that xenon-filled and argon-filled microbubbles will reduce neurodegeneration, protect cerebral vasculature, and improve behavioral outcomes through localized gas delivery to injured brain tissue. The microbubble approach enables targeted delivery using orders of magnitude lower gas amounts than current systemic xenon and argon therapies, potentially overcoming cost and availability barriers that have impeded clinical translation. The award period runs through August 31, 2029, with place of performance in New Jersey. The assistance type is a project grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $559.6k | 8/24/26 |