Project Grant R15HL177621

Award Date 1/15/25
Completion Date 12/31/27
Dollars Obligated $446K
Federal Grant Program
93.837
Assistance Type
Project Grant
Place of Performance
Ohio, USA
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The $445,500 award, effective January 15, 2025 through December 31, 2027, will enable CSU researchers to develop a recombinant TM/chondroitin sulfate glycosaminoglycan-liposome conjugate to study how membrane lipids affect the activation of protein C and thrombin-activatable fibrinolysis inhibitor (TAFI) by the TM/thrombin complex. This research aims to elucidate the independent or cooperative regulation of these two physiologically important pathways in the vasculature.

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