This $1,199,991 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program aims to develop novel technologies for real-time assessment of blood clot properties to improve stroke treatment. The key products and services under this grant include: Integration of a sub-millimeter Raman fiber probe into a catheter for intravascular, in-vivo measurement of clot chemical composition. Training of a convolutional neural network to...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $310,170 to Cathpro Technologies, LLC to develop an innovative luminal insert for vascular catheters. The goal is to create a product that combines anti-infective and anti-thrombotic technologies to effectively reduce intraluminal infections and thrombotic occlusions in catheters. The funding will support feasibility studies to optimize...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant of $275,000 awarded to Xtract Medical Inc. aims to develop and demonstrate the feasibility of a novel catheter-based system for improved removal of blood clots during mechanical thrombectomy procedures to treat venous thromboembolism (VTE). The proposed system is designed to effectively remove large blood clots while minimizing damage to blood vessels and reducing complications such as...
This $437,461 Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports the development of a novel stabilization catheter for His pacing lead implantation. The key product being developed is a sheath with a deployable suction flute that can improve the accuracy and ease of His lead placement for cardiac resynchronization therapy (CRT) in heart failure patients. The goal is to refine the sheath...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), part of the Cardiovascular Diseases Research program (CFDA 93.837), supports research to develop an ultrasound implant for monitoring spinal cord blood flow in patients with spinal cord injury (SCI). The $267,310 award to The Johns Hopkins University aims to quantify impaired autoregulation (the ability of blood vessels to regulate blood flow) around the SCI site using novel ultrasound techniques. The...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $449,122.00 to Trustees of Dartmouth College to develop a small, non-invasive device capable of mapping the intracranial space and differentiating ischemic from hemorrhagic stroke. The award aims to validate the feasibility of this novel approach to non-invasive...
This federal Project Grant award of $412,250.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support the development of a continuous, real-time, automated smart catheter analyzer for early identification of sepsis through urine biomarkers. The project, led by Arizona State University, aims to enable clinicians to quickly respond and support heart and lung function in sepsis patients. The smart catheter analyzer will be designed for use by...
This Project Grant, awarded by the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), aims to develop a unique antimicrobial vascular catheter to prevent catheter-related bloodstream infections (CRBSI). The $272,702 award, effective September 1, 2023, with a completion date of February 29, 2024, will support research and development efforts to create an intravascular catheter with inherent long-lasting antiseptic properties. The...
The National Heart, Lung, and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), awarded a $506,500 Project Grant under the Cardiovascular Diseases Research federal grant program (CFDA 93.837) to Endolynx Inc. in Jersey City, NJ. The project aims to develop an Optical Sensor-Enabled Endotracheal Tube (OS-ETT) to reduce the risks and costs associated with esophageal intubation and unintended extubation during the ~30 million intubations performed annually in the...
This federal Project Grant award of $131,191 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop a paradigm-shifting cuffless ambulatory blood pressure monitoring (ABPM) device. The key products and services to be delivered include: Designing an ultra-low-power and compact application-specific integrated circuit (ASIC) capable of performing duplex mode ultrasound for use in a soft, wrist-laminated, wireless...