Project Grant R15GM160955
Award Date 9/1/25
Completion Date 8/31/28
Dollars Obligated $532K
Funding Federal Agency
Awarding Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Kentucky, USA
Similar Awards
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded Kent State University a $546,146 Project Grant to study the structure, accessibility, and extension of telomeric overhangs. The five-year grant, running from February 1, 2025 to January 31, 2030, will utilize single-molecule fluorescence methods, cryo-electron microscopy, and ensemble techniques to investigate how the structure and stability of...
- This federal Project Grant award of $404,792 from the National Institute of General Medical Sciences (CFDA 93.859 - Biomedical Research and Research Training) to Yale University supports fundamental research to investigate the mechanisms regulating telomere length, protection, and replication. The research project aims to determine how the human POT1 protein coordinates the recruitment of telomerase and the CTC1-STN1-TEN1 complex to telomeres in order to maintain telomere length. Additionally,...
- This federal Project Grant award, provided by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program, supports research into the mechanisms that allow telomeres, the ends of chromosomes, to be protected from degradation and fusion that can lead to diseases like cancer. The $999,626 award to The Cleveland Clinic Foundation, commencing on Sep 1, 2025 and concluding on Aug 31, 2028, will investigate the role of the CCQ1 protein in shielding telomeres and...
- This Project Grant award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), provides $910,000 over 4 years to Weill Medical College of Cornell University to conduct research on the regulation of DNA repair mechanisms and transcription at telomeres. The research aims to improve understanding of how genetic information is protected at chromosome ends, which is critical for cell and organism health. The...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $1,000,000 to the University of Michigan provides funding from August 1, 2024 to July 31, 2028 to study the molecular mechanism of telomere maintenance in the model organism Caenorhabditis elegans. The research aims to leverage the simplicity of the worm's shelterin protein complex to answer fundamental questions about the structure and function of these proteins in chromosome end protection and...
- This $177,195 Project Grant award from the National Institute of General Medical Sciences (CFDA 93.859 - Biomedical Research and Research Training program) supports a research project at Western Kentucky University (WKU) examining the regulation of cellular morphogenesis in budding yeast. The project focuses on understanding how the Elm1 kinase coordinates with polarity and endocytosis factors to regulate the morphogenesis checkpoint and cell cycle progression. The research aims to provide...
- This Project Grant award from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) will provide $400,000.00 to Marshall University Research Corporation to conduct an integrated study on the relationship between telomere biology, flowering time regulation, and plant reproductive fitness. The 5-year project aims to elucidate the functional mechanisms linking telomere length and plant developmental traits, such as the timing of flowering initiation and seed production,...
- This federal Project Grant award of $380,070.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project titled "ACTIVE CHROMOSOME MOVEMENT IN MEIOTIC PAIRING" at the University of California, San Francisco (UCSF). The project aims to investigate the cellular mechanism of meiotic pairing, testing hypotheses regarding the role of telomere-led active motion and nuclear...
- This Project Grant award of $254,919.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research at the University of California, San Diego (UCSD) to investigate the regulatory mechanisms that ensure accurate transmission of the genome during cell division. Specifically, the research aims to study how post-translational modification enzymes regulate the assembly and function of DNA replication...
- This federal Project Grant award of $1,943,750.00, awarded on August 8, 2025, is provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports fundamental research and advanced training focused on understanding the molecular mechanisms that regulate the mitotic DNA damage response. The project, led by researchers at The Washington University, aims to 1) reveal how ubiquitinated histone H2A acts...