Project Grant R15EB037360
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $428,022 Project Grant to Arizona State University (ASU) for the "SEROGRAFT: A BIOINSPIRED ACELLULAR BIOMATERIAL FOR COMBATING TISSUE ADHESIONS" research project under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The grant, with a performance period from August 1, 2025 to July 31, 2027, aims to further engineer a novel, bio-derived...
- This federal Project Grant award for $1,339,647.00, provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a novel pressure-sensitive adhesive (PSA) system for minimally invasive surgery (MIS). The project, conducted by Brigham & Women's Hospital Inc. (a subsidiary of Partners Healthcare System), seeks to create an instant,...
- This federal Project Grant award of $454,155.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research at the University of Rochester to investigate the role of the S100A4 protein in the development and resolution of post-operative abdominal adhesions. The research aims to comprehensively define the molecular mechanisms underlying adhesion formation, determine...
- This $416,250.00 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" federal grant program (CFDA 93.286), supports research and development of novel in situ formed microneedle-like depots for spatiotemporally controlled drug delivery. The goal is to create a new drug delivery strategy based on intralesional printing of drug-eluting biomaterial...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $359,995 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to Clemson University. The funding supports the development and validation of a novel X-ray visualized immunosensor (X-VIS) that can be attached to implanted medical devices to detect and monitor local infection biomarkers. The project aims to fabricate a...
- This $395,695 federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) aims to develop novel multi-modal ultrasound imaging methods for non-invasive, real-time monitoring of tissue healing and early prognosis. The project will investigate new prognostic markers related to vascular and interstitial fluid transport mechanisms to assess...
- This Project Grant award of $117,562 from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports fundamental research to develop a new class of bioadhesive implants by Worcester Polytechnic Institute (WPI). The project aims to create a modular bioadhesive design integrating a liquid adhesive layer and a solid hydrogel layer, providing both strong, stable adhesion to target tissues and tissue-specific mechanical compliance. The research will...
- This federal Project Grant award of $296,746 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) aims to develop an intelligent adaptive closed-loop system called "CyberGut" that can identify and deliver optimized electrical stimulation to restore normal gastric motility in patients with gastric disorders. The key products to be developed under...
- This $384,863 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program supports research to develop a novel radiotracer imaging agent for detecting Gram-positive bacterial infections associated with implanted medical devices. The key products and services to be delivered include: In vitro testing of a bivalent radiotracer agent...
- This $705,182 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will develop and validate a specialized suite of Inflammation Digital Pathology Tools (IDPT). The IDPT will comprise new pathomics and machine learning models tailored for use in preclinical models of inflammatory bowel disease (IBD) and graft-versus-host disease...
This federal Project Grant award of $577,488.00 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), supports research and development of a novel microneedle-based, sandwiched structure for effective intraperitoneal adhesion (IA) prevention. The key objectives of the project are to: 1) Design and create a biodegradable sandwiched structure consisting of a core-shell electrospun nanofiber center and microneedle outer layers to prevent both early and late-stage IA formation and its extension following abdominal surgeries; and 2) Gain an in-depth understanding of the mechanisms involved in both early and late-stage IA formation and its extension, with a hypothesis that reactive oxygen species (ROS) play a pivotal role. The project aims to develop an effective mechanical barrier and explore the underlying molecular-level mechanisms to address significant challenges in IA prevention.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $577.5k | 8/11/25 |