This federal Project Grant award, titled "CAREER: MODULAR DESIGN OF BIOADHESIVES FOR IMPLANTATION", is funded by the National Science Foundation's (NSF) Mathematical and Physical Sciences (MPS) program (CFDA 47.049). The award, totaling $117,562, will support research to develop a new class of bioadhesive implants that integrate a liquid adhesive layer and a solid hydrogel layer. The goal is to create bioadhesives that provide fast, stable, and strong adhesion to target tissues...
This $962,735 cooperative agreement from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships program (CFDA 47.084) supports the development of an enhanced biodegradable tissue adhesive for gastrointestinal surgical wound closure applications by Bezwada Biomedical LLC. The small business will refine a polyurethane-based adhesive formulation and assess its in vivo performance to identify a safe, easy-to-use lead tissue adhesive that can help prevent...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering, under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program, is focused on validating the performance and acceptability of a novel adhesive acrylic negative pressure wound therapy (NPWT) drape developed by Global Biomedical Technologies LLC.
The $2,433,408 award will fund two randomized controlled trials to compare the performance of...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is providing $1,955,984.00 to Biodevek Inc., a small business based in Boston, MA, to develop a sprayable, biocompatible adhesive sealant called "GastroShield" for endoscopic management of gastrointestinal (GI) lesions and prevention of GI bleeding. The award supports key pre-clinical...
This federal Project Grant award of $582,301.00 from the National Institute of Biomedical Imaging and Bioengineering (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) supports the development of a novel 3D printing technology called "3D Printing of Air" (3DAIRP). This intangible ink technology can rapidly generate open, stable channels within yield-stress gels to enable the fabrication of vascularized tissues and organs. The project...
This federal Project Grant award for $389,211 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports research to study the fundamental mechanisms of gap closure during wound healing and tissue homeostasis.
The key objectives of this 5-year project are to: 1) rigorously characterize cell kinematics, proliferation, force distribution, and tissue fluidity during gap closure in tissues undergoing...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,353,337 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to The Johns Hopkins University. The goal of this 1-year project is to establish a new robotic system capable of performing autonomous soft tissue surgery, specifically for colonic anastomosis procedures. The funded work aims to develop novel 3D imaging, AI-based tissue...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering, under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program, is funding research and development of a novel wireless pressure sensor system to monitor intracranial pressure in patients with neurological conditions.
The $495,977 award supports the development and long-term in vitro testing of a membrane-based pressure microsensor...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering, under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program, aims to develop specifications for wearable haptic sensory prosthetic devices. The $173,700 award will fund research to (1) exploit attributes from both cutaneous and deep tissue sensation to communicate signal intensity levels, and (2) use 3D printed soft actuators and patterned...
The Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program provides $349,545 to support the development of the SAF-T-DRAPE, a sterile drapery shielding solution for radiological scanners. This innovation is designed to minimize hospital-acquired infections and improve efficiency in diagnostic radiology by addressing current limitations...
The federal Project Grant award R01EB035790, funded by the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program, aims to develop a novel pressure-sensitive bioadhesive (PSB) system for minimally invasive surgery (MIS). The $625,168 award, spanning March 2025 to November 2028, will enable the grantee, Brigham & Women's Hospital, to: 1) fabricate PSB materials with tunable viscoelastic and adhesive properties for different tissue types, 2) explore the PSB's performance for MIS applications, and 3) evaluate the feasibility of using PSB as a hemostatic adhesive and tissue stabilizer during endoscopic procedures. This research seeks to address the unmet need for effective wound closure and tissue retraction methods in MIS, which currently face challenges with traditional tools and adhesives. By developing an innovative PSB system that can instantly adhere to wet internal tissues, the project aims to enable atraumatic attachment and detachment of surgical equipment, minimize tissue damage, and enhance the adaptability of MIS procedures.