This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $306,872 to Bioprinting Laboratories Inc. to establish a platform for high-throughput developmental neurotoxicity (DNT) testing using engineered brain organoids. The key products and services to be delivered include: Developing genetically engineered, induced pluripotent stem cells with a promoter-reporter assay system to...
The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $135,000 Project Grant to the University of Central Florida (UCF) for the project "COLLABORATIVE RESEARCH: EAGER: 3D BIOPRINTED ORGANOIDS FOR STUDYING THE MECHANISM OF CEREBROVASCULAR AGING". This award supports the development of 3D bioprinted cerebrovascular organoids derived from human induced pluripotent stem cells to study the impact of cellular senescence...
This federal Project Grant award of $169,702 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286) will support the development and validation of a novel multiscale computational model to design and fabricate complex, spatially patterned tissue assembloids for biomanufacturing applications. The key objectives are to: 1) Develop a multiscale...
This federal Project Grant award of $629,031.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to develop a novel optical imaging technique called Optical Cell State Imaging (OCSI) that can track neural stem cell activation state in living cells without exogenous labeling. The key products and services to be delivered...
This Project Grant award of $449,228 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will fund the development of an integrated system for long-term electrophysiological profiling of human brain organoids. The key products and services to be delivered include: A biological assay chamber that supports chronic electrophysiology while maintaining the health of brain organoids. High-fidelity, 3D neural probes for chronic,...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Brainstorm Therapeutics, Inc. aims to develop and validate a novel Parkinson's disease drug discovery platform using patient-derived midbrain organoids. The platform will guide therapeutic candidate identification, patient selection, and trial endpoint refinement to accelerate the development of effective disease-modifying Parkinson's treatments. Key innovations...
This Project Grant awarded by the National Science Foundation (CFDA 47.041 - Engineering) provides $200,000 in funding to George Washington University to develop a 4D bioprinting technology platform for manufacturing soft robotic systems capable of targeted stem cell delivery. The project aims to create a versatile 4D bioprinting approach to produce custom living biosystems that can reshape in response to stimuli, enabling cargo loading and release as well as magnetic guidance to targeted...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program provides $769,352.00 to The Leland Stanford Junior University to develop an engineered bioprinting platform to study neural migration in brain assembloids. The goal is to create a more reproducible and physiologically-relevant in vitro model of interneuron migration for studying neurodevelopmental disorders. Key activities include evaluating...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant, awarded to Tissueform, Inc., a for-profit woman-owned small business in Boulder, Colorado, aims to develop a library of human-based bioinks for 3D bioprinting applications. The $274,822 award, with a performance period from September 2024 to August 2025, will focus on creating granulated bioinks for tissues such as cartilage, bone, skin, liver,...
This $387,104 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports the development of technologies for constructing 3D voxelated tissues with molecular architecture-encoded modular biomaterials. The award aims to enable a better understanding and control of stem cell function. Specifically, the grant will fund two research thrusts: (1) the development of modular bottlebrush gels to...