Project Grant 2317758
- This federal Project Grant award of $460,500 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) is aimed at developing novel bioprinting methodologies for the production of human stem cell-based organoids. The key objectives are to: 1) Create a customized bioink formulation using proteins, polysaccharides, and functionalized nanoparticles to foster the...
- This $299,844 Project Grant awarded by the National Science Foundation (NSF) under the STEM Education program (CFDA 47.076) supports the development of a microfluidic cortical organoid-vasculature platform at North Carolina Agricultural and Technical State University (NC A&T). The project aims to establish a new framework for "organoid-vasculature intelligence" by integrating the organoid platform with microelectrode array recording/stimulation and machine learning models. The...
- This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $304,906 to Seabird Lifesciences LLC for the development of a novel bioprinting approach to create vascular grafts. The project aims to produce a next-generation vascular graft that improves outcomes for patients undergoing vascular surgeries by enhancing tissue integration, improving long-term performance, and reducing the need for repeat...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Salk Institute for Biological Studies a $150,104 Project Grant effective February 1, 2026, through October 31, 2028, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This research project delivers scientific investigation and development of advanced in vitro methodologies for growing brain organoids with improved structural...
- This $199,988 National Science Foundation Engineering Research Initiation award will support the development of a 3D in vitro model to study the relationship between changes in brain tissue extracellular matrix composition and neuroinflammation. Specifically, the awardee, Trinity University, will fabricate multi-interpenetrating polymer networks comprised of fibrin, hyaluronic acid, collagen, and polyethylene glycol to mimic key changes in matrix content and study their effect on human astrocyte...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Brainstorm Therapeutics, Inc. aims to develop and validate a novel Parkinson's disease drug discovery platform using patient-derived midbrain organoids. The platform will guide therapeutic candidate identification, patient selection, and trial endpoint refinement to accelerate the development of effective disease-modifying Parkinson's treatments. Key innovations...
- This $484,314 Project Grant was awarded by the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences program (CFDA 47.074). The funding will support research at Christopher Newport University to investigate the "microbiota-gut-brain axis" and the impact of intestinal barrier dysfunction on aging and neurodegeneration. Key objectives include gaining insights into the cellular and molecular changes associated with an aging gut, how...
- The National Science Foundation (NSF) Engineering Directorate awarded a $564,510 Project Grant to the University of Massachusetts (UMass) to develop an engineered neural organoid system with improved brain regionalization and integrated mesh electrodes for enhanced monitoring and stimulation capabilities. The key objectives of this 3-year grant project are to: 1) Assemble regionalized neural organoids that enable thalamus-subpallium-cortex projections by stacking sliced organoids, 2) Innervate...
- Federal Grant Award Summary The National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation awarded the Board of Regents of the Nevada System of Higher Education (University of Nevada, Reno) an Early-Concept Grant for Exploratory Research (EAGER) project grant of $150,000 on August 1, 2025, with a completion date of July 31, 2027. Under the Engineering program (CFDA 47.041), this project will develop an embedded section-by-section bioprinting (ESB) process...
- The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $399,146 Project Grant to the Regents of the University of Michigan under the Engineering program (CFDA 47.041) to develop a bioreactor system for conducting research on the effects of microgravity and aging on neuromuscular function. The objectives are to evaluate force generation and reactive oxygen species production in tissue-engineered human nerve-muscle constructs,...
The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $135,000 Project Grant to the University of Central Florida (UCF) for the project "COLLABORATIVE RESEARCH: EAGER: 3D BIOPRINTED ORGANOIDS FOR STUDYING THE MECHANISM OF CEREBROVASCULAR AGING". This award supports the development of 3D bioprinted cerebrovascular organoids derived from human induced pluripotent stem cells to study the impact of cellular senescence on the cerebrovascular system. The goal is to create in vitro models that can mimic the aging process and associated neurodegenerative diseases, enabling more efficient research without lengthy in vivo experiments. This work will provide educational training opportunities, especially for underrepresented minority students in STEM fields, and support outreach activities. The award period is from August 1, 2023 to January 31, 2025.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $135.0k | 8/23/23 |