This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) provides $499,440 to ADA Forsyth Institute, Inc. to develop and evaluate biostable and multifunctional dental resin composites and adhesives that are superior in performance and durability to current methacrylate-based products. The project aims to formulate novel hybrid resin networks that resist hydrolysis and enzyme...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $441,500 Project Grant (CFDA 93.121 Oral Diseases and Disorders Research) to the University of Colorado-Denver to develop uniquely high conversion and mechanically robust composite restorative materials for improved dental applications. The award aims to investigate the structure-property relationships and mechanisms that enable these novel polymer composites to achieve exceptional strength, toughness, and wear...
This National Institute of Dental and Craniofacial Research (NIDCR) Oral Diseases and Disorders Research (CFDA 93.121) Project Grant award to East Carolina University (ECU) aims to develop innovative dental materials that can inhibit the formation of harmful bacterial biofilms while preserving beneficial oral bacteria. The $164,255 grant will fund research to synthesize a new antimicrobial agent, formulate it into methacrylate-based self-etch adhesive (SEA) dental materials, and evaluate the...
This $1,297,941 federal Project Grant award, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop a novel platform for rapid and precise creation of bioactive, multifunctional dental restoration materials. The key products and services being delivered through this grant include: Creating a self-improving dental adhesive that enhances its bond to tooth structure by facilitating...
The National Institute of Dental and Craniofacial Research (NIDCR), through its Oral Diseases and Disorders Research program (CFDA 93.121), awarded a $295,689 Project Grant to Callentis Consulting Group LLC, a woman-owned small business, to develop high-performance, bisphenol A (BPA)-free dental restoration composites with remineralization capabilities. The research, conducted in collaboration with the University of Colorado and New Mexico State University, aims to create innovative...
This $310,000 federal Project Grant award, funded by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop a novel primer for the reversible bonding and debonding of high-strength dental ceramics. The research seeks to address the challenges associated with the removal of all-ceramic dental crowns, which often requires destructive high-speed instrumentation that can compromise underlying tissue and...
This $800,000 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will support research to elucidate the role of matrix metalloproteinase 13 (MMP13) in regulating the dental pulp's reparative processes and inflammatory response. The key objectives are to determine how MMP13 influences tertiary dentin formation and modulates the immunological response in pulpitis, as well as to translate...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) totals $588,952 and will run from April 2025 to March 2030. The funding will support the development and optimization of a bio-inspired tubular matrix scaffold to guide the formation of periodontal ligament (PDL) principal fibers and rebuild the microenvironment for the regeneration of Sharpey's fibers, which are critical for...
The University of Kansas Center for Research Inc. was awarded a $467,008 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), to develop a novel non-invasive treatment for dental caries in children and patients with special needs. The project aims to create a biomimetic peptide-polymer interface that works synergistically with silver diamine fluoride (SDF) to arrest caries progression and...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $641,438 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The University of Iowa. The purpose of this 2-year award, effective May 13, 2024, is to develop and evaluate an innovative injectable chitosan hydrogel that can locally release the metabolite AKG to prevent and treat periodontitis-induced bone loss. The hydrogel is designed to simultaneously reduce bacterial infection,...