Project Grant R15AR084501
- The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a Project Grant of $413,655 on August 1, 2025 to Arizona State University (ASU) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant will fund research to develop biomaterials with temporal control of proteins, such as Bone Morphogenetic Proteins (BMPs), to enhance bone repair. The research aims to mimic natural extracellular matrix interactions and synergies...
- This federal Project Grant award of $570,174 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports the development and evaluation of a zonal-specific mineralized scaffold optimal for osteochondral (OC) tissue regeneration. The research aims to mimic the hierarchical microstructure and composition of native OC tissue, which consists of articular cartilage and subchondral...
- This $219,609 project grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is aimed at developing a method to assess mechanical failure of bone matrix using in vitro cell culture. The primary goal is to overcome the current challenge of requiring whole mouse bone specimens to detect changes in bone matrix mechanical properties, by using micropillars generated from...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $594,000 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to Poly Orth International to develop a 3D-printed "Skin and Bone Integrated Pylon" (SBIP) for direct skeletal attachment of limb prostheses. The research aims to demonstrate the feasibility and safety of this novel prosthetic technology, which can potentially benefit patients who...
- This $476,886 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research at Boston University to develop computational models for predicting the spatiotemporal distribution of growth factors in tissue engineering scaffolds. The goal is to optimize scaffold designs to achieve optimal growth factor exposure profiles that improve tissue regeneration outcomes, particularly for cartilage repair. The research utilizes reaction-diffusion...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is developing the X-Visual, a sensor to track fracture healing in cannulated screws used for hip fracture fixation. The $299,999 award to Aravis Biotech LLC will cover the design, computational modeling, and initial testing of this innovative device that can non-invasively measure screw bending...
- The National Science Foundation (NSF) Office of International Science and Engineering (CFDA 47.079) awarded a $420,000 Project Grant to Lehigh University to develop predictive computer simulation tools that can forecast bone healing progress for patients with poorly healing fractures. The 4-year project, running from October 1, 2025 to September 30, 2029, aims to create digital twin models of real bones using medical imaging data. These simulations will provide insights into individual healing...
- This CAREER: PRINTED MAGNETOELECTRIC COMPOSITES AS A BIOSCAFFOLD FOR BONE TISSUE ENGINEERING federal Project Grant, awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049), aims to develop a novel magnetically responsive biomaterial that can replicate the microstructures and physical stimuli of natural human bones. The $113,932 award, with a performance period from January 15, 2025 to December 31, 2029, will support research conducted...
- The University of Pittsburgh received a $158,555 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The grant is for the development and evaluation of a personalized, wireless, electronic-free metamaterial interbody fusion cage that can precisely measure forces during spinal fusion in-vivo and transmit the data wirelessly in real-time. The project...
- This $663,901 Project Grant was awarded on September 1, 2025 by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant supports Emory University's research to understand how the gut microbiome and T-cells influence fracture healing. The project aims to investigate how gut bacteria and immune cells, particularly Th17 cells, can be leveraged to improve fracture repair and...
This $430,152 Project Grant was awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award supports the development of a stand-alone simulation platform for designing tissue engineering scaffolds to serve as bone graft substitutes. The platform will leverage COMSOL software and JMP statistical design functionality to optimize the architecture and composition of 3D-plotted composite scaffolds made of slow-degrading and fast-degrading materials. This will enable non-domain specialists to design scaffolds with optimal biomechanical properties and porosity for bone tissue engineering applications. The project period runs from Aug 15, 2025 through Jul 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $430.2k | 8/14/25 |