Project Grant R15AI188433
- FEDERAL GRANT AWARD SUMMARY The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Washington a Project Grant totaling $2,306,555 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period February 1, 2026 through January 31, 2030. This award supports fundamental research investigating the molecular determinants and functions of bacterial polysaccharide cellular localization in Pseudomonas aeruginosa biofilms. The research will...
- Federal Grant Award Summary Princeton University's Office of Research and Project Administration received a $451,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 23, 2025, with completion targeted for June 30, 2027. The research initiative employs chemical synthetic lethality methodology to identify novel antimicrobial targets in gram-negative bacterial...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2027. The grant supports research to identify and develop novel anti-biofilm therapeutic agents by exploiting bacteriophage mechanisms that penetrate bacterial biofilm matrices. The research focuses on mining...
- Federal Grant Award Summary The University of Washington received a $445,338 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on July 23, 2025, with a completion date of June 30, 2027. This award supports research investigating the mechanisms of age-related lung inflammation in pulmonary melioidosis, a frequently fatal tropical infection caused by Burkholderia pseudomallei. The...
- Federal Grant Award Summary Northwestern University received a $240,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective September 5, 2025, through August 31, 2027. The grant supports investigator-initiated biomedical research focused on elucidating the mechanisms by which Pseudomonas aeruginosa (PA), a gram-negative bacterium responsible for over 400,000 deaths annually...
- Federal Grant Award Summary The University of California, San Diego received a $449,578 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), with an award date of February 1, 2026, and completion date of January 31, 2031. This five-year award supports investigator-initiated biomedical research exploring the role of lytic polysaccharide monooxygenases (LPMOs) in the virulence and immunity...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $638,220 Project Grant effective April 1, 2026, through March 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports investigator-initiated biomedical research examining DNA ADP-ribosylation mechanisms in bacterial-phage interactions. The research focuses on understanding how bacteria utilize DNA-targeting...
- Federal Grant Award Summary Northwestern University's Sponsored Research Division received a $431,784 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct investigator-initiated biomedical research on Pseudomonas aeruginosa (PA) gastrointestinal carriage mechanisms. The award, obligated on February 19, 2026, with a completion date of January 31, 2028, supports research utilizing an...
- Federal Project Grant Award Summary The University of Washington received a $229,870 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 23, 2025, with completion targeted for August 31, 2027. The award supports the development and validation of a plasma proteomic diagnostic tool for melioidosis, a tropical infection caused by Burkholderia pseudomallei with mortality rates...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $773,053 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective June 6, 2025, with a completion date of May 31, 2030. This research project focuses on elucidating the biosynthesis of beta-1,6-glucan in the cell wall of Cryptococcus neoformans, a fungal pathogen responsible for approximately 150,000 deaths annually,...
Eastern Washington University received a $470,978 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective April 9, 2026, with completion targeted for March 31, 2029. The award supports investigator-initiated biomedical research aimed at understanding the biosynthesis of aromatic virulence factors produced by Pseudomonas aeruginosa, an opportunistic pathogen responsible for numerous human infections and demonstrating significant antimicrobial resistance. The research project focuses on characterizing DAHP (3-deoxy-D-arabino-heptulosonate 7-phosphate) synthases, enzymes that catalyze the first committed step in bacterial aromatic compound biosynthesis. The deliverables include molecular-level characterization of how different DAHP synthase isoforms (PA1750, PA2943, PHZC1, and PHZC2) contribute to the production of phenazines and pseudomonas quinolone signal (PQS)—critical virulence factors in P. aeruginosa pathogenesis. The research findings are expected to generate scientific knowledge and alternative therapeutic approaches to combat this pathogen by potentially disrupting aromatic virulence factor production.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $471.0k | 4/9/26 |