This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $1 to support the development of a cell-type specific atlas of transcription factor-element connectivity across human tissues. The project aims to integrate single-cell and single-nucleus ATAC-seq data from the GTEx and HuBMAP Common Fund projects, and apply deep learning methods to predict transcription factor binding across these datasets. The goal is to characterize transcription factor binding and cis-regulatory element activity in human tissues and cell types, enabling the annotation of genetic variants associated with diseases and traits. The project will make all data, code, and model predictions publicly available through the Common Fund Data Ecosystem portal. The award was granted to the Broad Institute, Inc., a renowned biomedical and genomic research organization, and the project is expected to be completed by May 31, 2026.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $1 | 6/10/25 |