Project Grant R03HD121999
- Federal Grant Award Summary The University of Wisconsin-Madison received a $116,685 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 1, 2025, through August 17, 2027. This award supports a two-phase research initiative examining cancer survivorship needs and reintegration outcomes for children with Down Syndrome (DS) who are in remission from...
- Federal Grant Award Summary The University of Wisconsin-Milwaukee is receiving $563,880 in federal funding under a Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) through the Biomedical Research and Research Training program (CFDA 93.859). The award, effective September 1, 2025, through August 31, 2028, supports fundamental research into the regulators of the unfolded protein response (UPR) signaling pathway. The research will investigate how the three major...
- Federal Project Grant Award Summary The University of Wisconsin–Madison received a $155,500 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 1, 2025 through August 31, 2027. The research project investigates the relationship between parent-child relationship quality and pre-vocational skills development in autistic youth, addressing the critical...
- Federal Grant Award Summary The University of Wisconsin–Madison received a $1,542,150 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 10, 2025, with completion targeted for May 31, 2030. The award funds research investigating the developmental factors underlying the approximate number system—a foundational cognitive ability enabling young...
- Federal Project Grant Award Summary The University of Wisconsin-Madison received a $580,507 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded May 6, 2026, with completion targeted for February 28, 2031. This five-year research initiative investigates the mechanisms governing midbody remnants (MBRs)—large extracellular vesicles released during cell division—as mediators of...
- Federal Grant Award Summary The University of Wisconsin–Madison received a $149,294 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective July 4, 2025, through June 30, 2027. The award supports basic neuroscience research investigating the mechanisms of ZIC2 function in zebrafish forebrain development, with particular focus on...
- Federal Project Grant Award Summary The University of Wisconsin-Madison received a $414,305 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded March 1, 2026, with a completion date of February 28, 2031. This five-year initiative will develop and implement advanced statistical genetics tools designed to improve drug target discovery and treatment optimization. The project addresses...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded a $462,538 Project Grant to Magee-Womens Research Institute and Foundation under the Child Health and Human Development Extramural Research program (CFDA 93.865) for the period of June 1, 2026 through May 31, 2028. The award funds research investigating CHD7-dependent regulation of migration and morphogenesis in the context of CHARGE syndrome, a congenital developmental disorder...
- Federal Grant Award Summary The University of Miami's Office of Research Administration received a $664,101 Project Grant from the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865) on June 1, 2026, with a completion date of May 31, 2031. This investigator-initiated research award supports a five-year study investigating the impact of disease-associated mutations in the Polycomb system, specifically...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded the University of Massachusetts Medical School $460,625 under the Child Health and Human Development Extramural Research program (CFDA 93.865) on June 1, 2026, with completion targeted for May 31, 2028. This project grant supports the development of prime editing therapeutics for Limb Girdle Muscular Dystrophy R9 (LGMDR9), a rare genetic disorder caused by mutations in the FKRP...
The University of Wisconsin–Milwaukee received a $144,064 project grant awarded June 1, 2026, through the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports a two-year research project (completion date May 31, 2028) investigating how pathogenic genetic variants associated with rasopathies—specifically Noonan Syndrome and Cardiofaciocutaneous Syndrome—alter RAF protein function and actin-myosin cytoskeleton regulation. Using Caenorhabditis elegans as a model organism, researchers will assess subcellular localization, protein levels, and kinase activation of RAF in animals carrying rasopathy variants and test the effects of hyperactive RAF on actin-myosin contractility and cytoskeleton protein organization. The research aims to identify novel cellular targets of RAF signaling that could inform future drug design and discovery strategies targeting RAF kinase inhibition. By characterizing how different rasopathy genetic variants produce distinct consequences to RAF protein localization while potentially sharing common effects on the actin-myosin cytoskeleton, this project will advance understanding of the molecular mechanisms underlying these developmental disorders and potentially enable identification of promising therapeutic targets for treatment intervention.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $144.1k | 6/2/26 |