Project Grant R03ES037408
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $419,375 under the Environmental Health program (CFDA 93.113) on August 10, 2026, to explore nanoplastics' neurological effects through investigation of lipid mechanisms and glial inflammation. The recipient will conduct research on micro- and nanoplastics bioaccumulation in the human brain and their molecular interactions within cerebrospinal fluid and the central nervous...
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $167,928 under the Environmental Health Project Grant program (CFDA 93.113) on April 1, 2026. The project investigates lipoprotein-mediated nanoplastic uptake and transport across the placenta. The research addresses how micro and nanoplastics translocate into placental tissue and the role chylomicrons may play in facilitating this process. The working hypothesis posits that...
- The National Institute of Environmental Health Sciences awarded the Board of Regents of the University of Nebraska $1,479,178 on September 9, 2025, under the Environmental Health program (CFDA 93.113) to quantify the release of nano- and microplastics from plastic food containers into water and beverages and assess potential health risks. The project measures the release of nano- and microplastics from reusable plastic cups, single-use water and soft drink bottles, and takeaway coffee cups...
- The National Institute of Environmental Health Sciences awarded New York University $10.907 million on September 15, 2025, under the Environmental Health program (CFDA 93.113) to conduct a translational study on the accumulation of micro- and nanoplastic particles in mammalian tissues. The research investigates inter-tissue accumulation of micro- and nanoplastic particles across the lifespan, including the quantified concentration of these particles within systemic tissues, the role of sex, age,...
- The National Institute of Environmental Health Sciences awarded New Mexico State University $177,460 on August 17, 2026, under the Environmental Health program (CFDA 93.113) to investigate the prevalence and health risks of per- and polyfluoroalkyl substances (PFAS) in New Mexico de facto water reuse systems. The project addresses PFAS contamination in drinking water sources resulting from de facto reuse of treated wastewater—the unintentional introduction of treated wastewater into downstream...
- The National Institute of Environmental Health Sciences awarded New York University $497,998 on June 2, 2026, to investigate the epigenetic and genetic regulation of arsenic methylation and arsenic-related cardiovascular disease risk in Native American populations under the Environmental Health program (CFDA 93.113). The research examines how DNA methylation and microRNAs influence arsenic biomethylation efficiency and downstream cardiovascular disease risk, leveraging biospecimens and...
- The National Institute of Environmental Health Sciences awarded the University of Cincinnati $698,212 on April 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate the impact of micro- and nanoplastics on cardiac toxicity and heart disease susceptibility. The research addresses mechanisms by which micro- and nanoplastics cause cardiac damage, focusing on mitochondrial dysfunction and oxidative stress in the heart. Preliminary findings show that exposure to micro- and...
- The National Institute of Environmental Health Sciences awarded $765,348 to the University of California, Davis on April 14, 2026, under the Environmental Health program (CFDA 93.113) to investigate pollutant-adsorbed nanoplastics and their health impacts following inhalation exposure. The research addresses the formation, distribution, and neurotoxic effects of composite particles created when airborne pollutants adsorb onto nanoplastics. The study employs advanced label-free imaging...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $429,504 to New York University (NYU) School of Medicine to characterize human exposure to microplastics during pregnancy. The overarching aim is to leverage existing infrastructure from the NYU Children's Environmental Health Study (NYU CHES) to measure and characterize microplastics in placental tissue collected from the general...
- The National Institute of Environmental Health Sciences awarded $114,072 to Rutgers The State University of New Jersey, School of Nursing, on September 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate mechanisms of micro-nanoplastics uptake, translocation, and toxicity in in vitro human intestinal models. The research explores how micro-nanoplastics—small plastic particles from environmental breakdown of waste—enter and cross biological barriers, particularly the...
The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $152,500 on August 15, 2026, under the Environmental Health program (CFDA 93.113) to define dose-response relationships and renal functional impairment from simultaneous exposure to micro- and nano-plastics and arsenic. The research establishes a quantitative framework for how micro- and nano-plastics behave when co-present with arsenic in the body, whether their excretion is dose-proportional, how much accumulates in renal tissue, and whether co-exposure produces synergistic impairment of glomerular filtration rate. Aim 1 defines dose-response, excretion kinetics, and mass balance of arsenic, polyethylene terephthalate (500 nm), polystyrene (15 nm), and environmentally collected micro- and nano-plastics from Christmas Island in mice using metabolic cages and multiple orthogonal detection platforms. Aim 2 determines whether repeated micro- and nano-plastic and arsenic exposures produce renal functional decline using non-invasive FITC-sinistrin glomerular filtration rate monitoring and urinary injury biomarkers. Aim 3 identifies renal injury pathways using bulk RNA sequencing in kidneys with 20 percent glomerular filtration rate loss versus controls. The award runs from August 15, 2026, through August 14, 2028, with place of performance at Albuquerque, New Mexico.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $152.5k | 8/12/26 |