Project Grant R03EB036835

Award Date 8/1/25
Completion Date 7/31/27
Dollars Obligated $165K
Federal Grant Program
93.286
Assistance Type
Project Grant
Place of Performance
Charlestown, MA 02129, USA
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The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,360,447.52 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop and evaluate an inexpensive, lightweight "brain monitor" device using magnetic resonance imaging (MRI) technology. The goal is to create a portable MRI-based...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,758,475 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop next-generation in-vivo diffusion MRI (DMRI) technologies. The project aims to overcome key challenges with current DMRI methods, including lack of sensitivity to detect...
The federal Project Grant award in the amount of $999,940.00 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), for the project "DEVELOPMENT OF IMAGING OUTCOME MEASURES OF NEUROPROTECTION IN MULTIPLE SCLEROSIS USING ULTRA-HIGH GRADIENT DIFFUSION MRI". The award period is from June 1, 2024 to May 31, 2027. Through this grant, MGH...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $3,565,780 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop a groundbreaking high-frequency trans-spinal magnetic stimulation (HF-TSMS) system for the non-invasive treatment of neuropathic pain. The funded project aims to create an HF-TSMS tool that can target neural pathways involved in...
The Department of the Army Medical Command awarded a $711,403 project grant to The Children's Hospital Corporation (doing business as Boston Children's Hospital) under the Military Medical Research and Development program (CFDA 12.420). The grant supports a project titled "A Noninvasive Neurotrophic Factor Treatment to Repair the Injured Spinal Cord" with a period of performance from October 1, 2024 to September 30, 2027. This project grant supports advanced biomedical research focused...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $185,625 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to develop a novel magnetic resonance imaging (MRI) technology. The technology aims to address the flip angle inhomogeneity problem in high-field 7 Tesla MRI through the...
This federal Project Grant award of $325,142, provided by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, supports the development of a clinical-grade spinal cord neuroprosthesis to alleviate locomotor deficits in people with Parkinson's disease. The award, which has a performance period from September 1, 2025 to August 31, 2028, is being provided to Onward Medical Inc., a for-profit organization located in Boston, MA. The goal of this...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $151,559 to Rensselaer Polytechnic Institute (RPI) from August 3, 2024 to July 31, 2026. The project aims to develop innovative magnetically responsive drug delivery electrospun fibers to improve regeneration after spinal cord injury (SCI). Specifically, the research will focus...
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This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $798,848.00 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to investigate the role of the skull bone marrow niche in post-stroke inflammation and recovery. The project aims to examine the information transfer between the central nervous...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $165,000.00 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to conduct research on magnetic spinal cord stimulation (MSCS) for motor rehabilitation. The project aims to assess the safety, tolerability, and potential of MSCS as an alternative, less invasive technique to conventional spinal cord stimulation for direct spinal cord stimulation and motor rehabilitation, particularly after spinal cord injury. The research program involves bioelectromagnetic modeling, hardware optimization, and experimental validation through a healthy volunteer study. This effort is expected to run from August 1, 2025 to July 31, 2027.

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