Project Grant R03EB026036

The National Science Foundation (NSF) Division of Chemistry awarded a $480,000 Project Grant to Virginia Commonwealth University (VCU) to improve the separation of complex biological samples by exploring the use of mixed-mode gradient stationary phases for liquid chromatography (LC). This 3-year project, funded under the Mathematical and Physical Sciences program (CFDA 47.049), aims to develop new approaches to strategically modify particle-packed silica columns with functionalized...

The National Science Foundation (NSF) Division of Chemistry awarded a $290,000 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the Regents of the University of Minnesota to develop accurate molecular models for chromatographic systems. This 2-year collaborative research aims to: (i) predict retention orders in chromatographic systems without adjustable parameters, (ii) provide microscopic-level insights into separation processes, and (iii) utilize this...

The National Science Foundation awarded Deleon Technologies, Inc. $305,000 on July 1, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a low-cost, single-use microfluidic chip that performs capillary electrophoresis with laser-induced fluorescence detection for daily personalized metabolomics monitoring. The project will validate the feasibility of manufacturing a disposable microchip capable of automated chemical analysis of urine in minutes at home,...

The National Science Foundation Division of Chemistry awarded $822,518 to the University of Kansas Center For Research Inc. on January 15, 2027, to fund planar capillary electrophoresis research under the Mathematical and Physical Sciences program. Professor Robert Dunn and his group are developing cost-effective approaches for rapidly analyzing complex mixtures using capillary electrophoresis with laser-based refractive index detection. The project integrates single-molecule scattering...

This $390,000 federal Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports research led by Professor Yong Guo and his team at Fairleigh Dickinson University (FDU) to develop a new methodology for quantitatively evaluating the retention mechanisms in hydrophilic interaction chromatography (HILIC). The goal is to better understand the complex separation principles behind HILIC, which is widely used in biomedical...

Grant Award Summary Washington State University, under the direction of Professor Brian H. Clowers, received a $485,838 Project Grant award from the National Science Foundation's Division of Chemistry (CFDA 47.049 – Mathematical and Physical Sciences) effective September 1, 2025, through August 31, 2028. The grant supports the development of a novel analytical platform for advancing chemical separations through multimodal ion chemistry and tandem ion mobility spectrometry. The research team will...

This Project Grant award, provided by the National Science Foundation's (NSF) Engineering Program (CFDA 47.041), aims to improve the fundamental understanding of chromatographic separation processes at the nanoscale. The $201,000 grant, with a period of performance from January 1, 2025 to December 31, 2027, will enable an international team of researchers from the United States and Germany to directly observe the dynamic interactions between functionalized nanoparticles and chromatographic...

Grant Award Summary The National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), awarded $442,515 to Gustavus Adolphus College for a three-year project (August 1, 2025 – July 31, 2028) titled "GOALI: Technologies to Support the New Era of Liquid Chromatography Research." This academic-industry collaboration with Agilent Technologies, led by Professor Dwight Stoll, focuses on developing innovative technologies in two...

This $337,863 Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049) supports research by Professor Ken Marcus and his team at Clemson University to develop new methods for isolating and purifying diverse biological nanoparticles, including exosomes, lentiviruses, and adeno-associated viruses. The researchers aim to characterize and implement a unique fiber-based stationary phase,...

This federal Project Grant award, provided by the National Science Foundation's (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041 - Engineering), supports collaborative research by an international team of scientists from the U.S. and Germany. The $273,999 award, granted to The Trustees of Princeton University, aims to shed new light on the interfacial layer dynamics that occur during the chromatographic separation of nanomaterials. The research team...