The National Science Foundation Division of Chemistry awarded $822,518 to the University of Kansas Center For Research Inc. on January 15, 2027, to fund planar capillary electrophoresis research under the Mathematical and Physical Sciences program.
Professor Robert Dunn and his group are developing cost-effective approaches for rapidly analyzing complex mixtures using capillary electrophoresis with laser-based refractive index detection. The project integrates single-molecule scattering measurements to push detection limits to the single-molecule level, enabling label-free detection of analytes ranging from small inorganic ions to large proteins without labels or contrast agents. Graduate and undergraduate students will combine this optical detection method with capillary electrophoresis to create an all-optical mass detector for rapid separations. The work leverages short fused silica capillaries (10 centimeters total length with closely matched inner and outer diameters) to enable rapid separations while reducing Joule heating effects through improved heat dissipation.
Performance occurs in Lawrence, Kansas, with a period of performance extending from the award date through December 31, 2030. The assistance type is a Project Grant.