Project Grant R03DK147560
- Federal Grant Award Summary Yale University received a $1.33M Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for the period June 1, 2025 through May 31, 2029. The award funds basic biomedical research investigating the compensatory mechanisms by which pancreatic alpha-cells (A-cells) preserve insulin secretion and glycemic control in response to...
- Federal Grant Award Summary Yale University received a $133,333 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), with an award date of September 15, 2025 and completion date of August 31, 2026. The funded research aims to develop interventions to correct the myeloid bias of aged hematopoietic stem and progenitor cells (HSPCs) by preventing linker...
- Federal Grant Award Summary Yale University received a $193,809 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective August 1, 2025 through April 30, 2030. The award supports clinical research investigating the efficacy and safety of sodium-glucose cotransporter-2 inhibitors (SGLT2i) for treating acute cardio-renal syndrome (CRS), a condition where...
- Federal Project Grant Award Summary Yale University received a $172,622 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded on June 17, 2025, with a completion date of January 31, 2029. The research project, conducted at Yale's New Haven, Connecticut facility, focuses on elucidating the role of cyclin G-associated kinase (GAK) as a regulator of...
- Federal Grant Award Summary Brigham Young University received a $568,075 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective July 1, 2025 through June 30, 2028. The award funds basic biomedical research designed to elucidate the role of the NR4A1 protein in beta-cell expansion pathways, with the objective of identifying therapeutic targets for...
- Federal Project Grant Award Summary Yale University received a $802,843 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded September 13, 2025, with completion targeted for June 30, 2030. The research will investigate the pathogenic mechanisms linking obesity to cardiometabolic complications in pediatric populations, with specific focus on how...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Scripps Research Institute a $801,662 Project Grant effective August 15, 2025, through June 30, 2029, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research project investigates the initiation of anti-islet autoimmunity in Type 1 Diabetes (T1D), a CD4 T cell-mediated autoimmune disease, with particular focus on understanding the role...
- Federal Grant Award Summary Yale University received a $193,874 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective April 1, 2026, through December 31, 2030. The award funds a patient-centered research initiative to improve treatment outcomes for urinary incontinence (UI) among women with comorbid obesity and type 2 diabetes mellitus (T2DM)....
- Federal Project Grant Award Summary Yale University received a $3.23 million Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for the period September 1, 2025 through August 31, 2029. The award supports investigator-initiated biomedical research aimed at improving understanding of disease mechanisms and developing improved prevention, diagnosis, and...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Yale University a $309,386 Project Grant effective May 1, 2025, through February 28, 2030, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). This mentored career development award supports Dr. Brisa Palikuqi's research investigating the role of blood endothelial cells in intestinal regeneration and repair following injury, as well as...
Yale University received a $167,916 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for the period May 1, 2026 through April 30, 2028. The award supports research investigating genetic dysregulation of messenger ribonucleic acid (mRNA) translation in Type 1 Diabetes (T1D). The research project aims to advance understanding of how genetic variations affecting mRNA translation in pancreatic beta cells contribute to T1D disease development and progression, with particular focus on the role of RPS26 (Ribosomal Protein S26) expression in orchestrating noncanonical mRNA translation that may generate autoantigens driving beta cell destruction. This research addresses a critical gap in T1D molecular mechanisms by examining intrinsic beta cell biology as a driver of disease, complementing existing therapeutic approaches that primarily target T cells. The project outputs will include scientific findings on genetic contributions to beta cell vulnerability, identification of translation-based disease mechanisms, and potential translational insights applicable to developing novel therapeutic interventions for T1D prevention and treatment. Research activities are conducted at Yale University's New Haven, Connecticut facility.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $167.9k | 4/21/26 |