Project Grant R03DK145965
- Federal Project Grant Award Summary The University of Pittsburgh received a $521,829 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded on September 4, 2025, with completion targeted for June 30, 2029. This research project investigates hepatic prolactin receptor (PRLR) signaling and its role in maternal metabolic adaptation during pregnancy. The...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded UCLA a $786,216 project grant effective August 28, 2025, through June 30, 2029, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research investigating post-transcriptional regulation of hepatokines—secreted liver peptides that coordinate systemic metabolism—and their role in metabolic homeostasis. The research employs...
- Federal Project Grant Award Summary Baylor College of Medicine received a $231,708 Project Grant awarded on September 1, 2025, from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award, extending through April 16, 2028, supports biomedical research investigating the implications of iron homeostasis and ferroptosis in early pregnancy and endometriosis. The research addresses how...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded the University of Illinois a $689,134 Project Grant effective August 7, 2025, through the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a prospective, double-blind, placebo-controlled randomized clinical trial investigating the efficacy of probiotic supplementation in optimizing iron status among pregnant individuals at risk of iron deficiency...
- Federal Project Grant Award Summary Vanderbilt University Medical Center received a $143,346 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded July 15, 2025, with completion scheduled for May 31, 2030. The award funds transdisciplinary research addressing gestational weight gain and maternal-child health outcomes. The research delivers three...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a Project Grant of $239,213 to the University of California, San Diego, effective September 1, 2025, through August 31, 2027, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). This research initiative investigates the interface between glucocorticoid signaling and histone acetylation in erythropoiesis, with the goal of identifying new...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded UCLA a $761,399 Project Grant effective September 1, 2025, through June 30, 2030, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). This award funds basic biomedical research investigating the mechanisms that regulate lipid absorption in the gastrointestinal tract, with a specific focus on how immune cell lipid metabolism influences...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $390,000 Project Grant to the University of Colorado-Denver on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for research extending through June 30, 2030. The award supports basic biomedical research investigating a novel mutation in the TASPASE1 gene and its role in inherited bone marrow failure syndromes (IBMFS)....
- Federal Grant Award Summary The University of Colorado-Denver received a $129,619 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 1, 2025, through May 31, 2030. This research initiative delivers scientific investigation into the interactions between gut microbiome composition, intestinal development, and metabolic health...
- Federal Grant Award Summary New York University School of Medicine received a $1.5M Project Grant from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), awarded September 10, 2025, with completion targeted for August 31, 2028. This NIH New Innovator Award funds biomedical research investigating small intestinal tissue remodeling across pregnancy cycles to establish fundamental mechanistic understanding of how maternal...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the University of California, Los Angeles a $118,125 Project Grant (CFDA 93.847: Diabetes, Digestive, and Kidney Diseases Extramural Research) effective February 1, 2026, through January 31, 2028. This research grant supports the identification of placental iron-regulatory hormones and their role in maintaining iron homeostasis during pregnancy. The project delivers investigative services focused on identifying novel hepcidin suppressors produced by the trophoblast through high-throughput complementary DNA (cDNA) overexpression screening of over 600 candidate proteins isolated from human trophoblast supernatant and placental interstitial fluid. Additionally, the research characterizes the physiological role of hepatocyte growth factor (HGF) in hepcidin suppression during pregnancy. The research directly addresses a critical maternal health need, as inadequate iron availability during pregnancy is linked to adverse outcomes including increased maternal mortality, perinatal death, and preterm birth. By elucidating the mechanisms responsible for pregnancy-related hepcidin suppression—essential for maximizing dietary iron absorption and mobilization for fetal development—this project generates scientific knowledge and technical findings to advance understanding of iron metabolism in pregnancy and inform future therapeutic interventions.Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $118.1k | 1/30/26 |