This $631,896 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to compare different remote-based behavioral weight loss interventions and identify factors that characterize treatment response. The award will fund a 2x2 factorial study to evaluate the effectiveness of an automated online program vs. a group-based videoconference program, as...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $148,568 to support research investigating the physiological regulation of energy intake during meals following weight loss. The award will fund a study to analyze energy balance and gut hormone data from the ARROW Study (R01DK114272) and the TIME2EAT Study (R01DK132372) to better...
This Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund a study to analyze the impact of federal funding for obesity prevention programs on weight-related health behaviors, obesity prevalence, and obesity-related chronic conditions. The $340,175 award, which runs from September 1, 2024 to June 30, 2029, will leverage variation in which...
The federal Project Grant award K23DK138261, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under CFDA Program 93.847 "Diabetes, Digestive, and Kidney Diseases Extramural Research", provides $539,220.00 to support research on the mechanisms underlying sustained weight loss after bariatric surgery. The key objectives are to: (1) establish rapid intestinal nutrient delivery as a primary driver of the gut endocrine response to bariatric surgery, (2)...
This federal Project Grant award for $390,000 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will support research to investigate the role of the inward rectifier potassium channel KIR7.1 in regulating energy homeostasis and its potential as a therapeutic target for obesity. The research project, conducted by the Regents of the University of...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $506,598.00 to President and Fellows of Harvard College, through its Harvard T.H. Chan School of Public Health, to conduct fluxomics studies on the effects of dietary fat and carbohydrate composition on energy metabolism processes. The 1-year project, with a start date of September 15,...
This Project Grant award for $502,233 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports research at the University of Michigan to investigate neuron populations in the nucleus of the solitary tract (NTS) that mediate both aversive and non-aversive suppression of food intake. The researchers aim to use molecular genetic techniques to...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to investigate the role of activin type II receptor signaling in regulating muscle hypertrophy, obesity, and weight loss. The total funding amount is $2,060,811.00 for the project period from December 1, 2024 to November 30, 2029. The primary objectives are to explore how activin type II...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $674,391 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Mayo Clinic to conduct a 12-month randomized clinical trial. The study aims to compare the outcomes of a phenotype-tailored lifestyle intervention (PLI) program versus a standard lifestyle intervention (SLI) program for treating obesity in adults. Specifically, the project will: 1) Compare...
This federal Project Grant award of $538,357.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award aims to define the molecular regulation and physiological role of a novel lysosomal mechanism of adipocyte lipolysis. The research seeks to leverage innovative methods, including in vivo studies, multi-omics analyses, and high-resolution imaging mass...