The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $441,500 Project Grant (CFDA 93.121 Oral Diseases and Disorders Research) to the University of Colorado-Denver to develop uniquely high conversion and mechanically robust composite restorative materials for improved dental applications. The award aims to investigate the structure-property relationships and mechanisms that enable these novel polymer composites to achieve exceptional strength, toughness, and wear...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $421,800 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Midwestern University. The purpose of this 3-year grant, with a start date of September 7, 2023, is to develop hybrid hydrogel-based dental adhesives that are less vulnerable to hydrolytic degradation compared to current methacrylate-based alternatives. The goal is to create a truly biomimetic dental adhesive that can not only...
This $1,999,789 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) aims to advance oral health equity through strengthening the scientific basis for innovations in population approaches to improving dental care access, utilization, and quality. The research program will incorporate a framework that integrates multi-level perspectives and approaches (e.g., patient, provider, and...
This $433,125 Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, will fund research to investigate the potential biological factors underlying the association between adverse childhood experiences (ACEs) and dental caries in children. The study aims to examine the relationships among ACEs, the oral microbiome, dental caries, and salivary stress and immunological biomarkers in children....
This federal Project Grant award of $503,648 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research to investigate the genetic mechanisms driving the specification of oral/dental and skin lineages in the mandibular ectoderm. The research aims to determine how transcription factor interactions regulate these epithelial patterning processes, including identifying the chromatin-level regulation...
This federal Project Grant award of $319,624.00, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research to assess the marginal associations between dental caries and periodontal diseases and their determinants. The key products and services to be delivered under this 2-year grant include: 1) developing statistical tests to evaluate the informativeness of the number of observed teeth...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $157,500 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Ohio State University to conduct research on the cellular mechanisms regulating tooth development. The research aims to determine how the signaling molecule SEMA7A influences the mineralization of dentin, elongation of tooth roots, and innervation of teeth. The study will use global and conditional SEMA7A knockout mouse...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,325,889 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the University of Southern California on September 19, 2024. This grant, titled "Regulating Skeletal Connectivity in Craniofacial Development and Disease," will support a comprehensive and forward-thinking research program led by Dr. Amy Merrill that investigates the craniofacial skeleton as a multi-tissue...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $2,539,292 project grant under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121) to the ADA Forsyth Institute, Inc. (The Forsyth Institute) to develop a novel operational platform and suite of multifunctional dental restoration materials. The key products and services to be delivered include: Creating a self-improving, universal dental adhesive that enhances its bond to tooth structure through...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $150,989 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to The Research Foundation for The State University of New York, doing business as Stony Brook University. The goal of this 2-year project is to develop an automated tool to detect and characterize arterial calcifications in dental cone beam computed tomography (CBCT) scans. This research aims to establish quantifiable imaging...