Project Grant R03AI196408
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant totaling $429,000.00 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Regents of the University of Colorado at Denver for the development and comprehensive characterization of the MAIT-Boost Knock-In (MBKI) mouse model. The award, issued February 1, 2026, with an ultimate completion date of January 31, 2028, supports research to create a novel...
- Federal Grant Award Summary The University of California, San Diego received a $159,500 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025 through June 30, 2027. The award funds the development and validation of a novel transgenic mouse model that combines a B6.TCRA-AMCY reporter mouse with an established NUR77-GFP reporter model to measure T cell receptor...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $456,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period of April 1, 2026 through March 31, 2028. The project, titled "Defining a Minimal Sequential Infection Model to Mature Mouse Immune Responses," delivers research outputs focused on developing a standardized,...
- Federal Project Grant Award Summary The University of California, San Francisco received a $174,824 Project Grant award dated April 6, 2026, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award funds the development and characterization of a humanized interleukin-33 (IL-33) mouse model, which will integrate the human IL33 gene sequence—including approximately 28 kilobases of upstream...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $161,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 1, 2026, with completion targeted for March 31, 2028. The award funds the development of new genetic tools—specifically novel Cre and CreERT2 transgenic mouse models—for selective targeting and study of plasma cells...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant of $426,938 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 23, 2025, with a completion date of May 31, 2027. The award supports the development of a simplified, cost-effective mouse model of chronic Mycobacterium abscessus lung disease using BALB/c mice that requires only weekly cyclophosphamide administration. This...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $431,750 to the University of California, Irvine under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year developmental project commencing July 1, 2025 and concluding June 30, 2027. This Project Grant supports the development of a basic immunological toolbox for the genus Peromyscus, specifically targeting white-footed deermice (Peromyscus leucopus) and related...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $417,845 to the University of Nebraska Medical Center under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 9, 2025, for a project period extending through June 30, 2027. The award supports research to identify novel immune determinants influencing Staphylococcus aureus biofilm infection using Collaborative Cross (CC) mouse lines. The research addresses gaps in...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases awarded the University of Arizona a Project Grant totaling $368,681 (awarded May 13, 2026; completion date April 30, 2031) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to establish and expand the National Summer Undergraduate Research Project (NSURP). This eight-week virtual summer research program matches underrepresented minority undergraduate students nationwide with faculty...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3.1 million Project Grant to the University of California, Los Angeles under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 16, 2025, with a completion date of June 30, 2029. This award funds research to evaluate the mechanisms underlying immunosuppression induction and maintenance impacts on T cell function following kidney transplantation. The research employs...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Arizona a Project Grant totaling $155,479 on June 5, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for development of immune evasive transgenic mouse models to support transplantation research. The two-year project, concluding May 31, 2028, will generate specialized mouse models designed to overcome immunological barriers to organ and tissue engraftment by incorporating Cre recombinase-inducible gene modules that suppress complement deposition and membrane attack complex formation, express single chain peptide-B2M-MHC (major histocompatibility complex) trimers to inhibit natural killer cell activity, and express CD47 to engage inhibitory SIRPA receptors. These transgenic mouse models will serve as donor animals for standardized and controlled testing of immunological pathways critical to transplantation success. The deliverables from this award will provide research tools and preclinical models enabling systematic investigation of allogeneic rejection mechanisms and informing parallel genetic modifications in stem cells for regenerative medicine applications. By establishing these standardized transgenic models, the research will advance the scientific foundation for developing immunologically compatible cellular and tissue therapies. The project will be performed at the University of Arizona's facility in Tucson, Arizona.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $155.5k | 6/4/26 |