Project Grant R03AI196378
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Duquesne University a Project Grant of $507,121 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 21, 2025. The award supports a three-year research initiative (completion date: July 31, 2028) focused on elucidating the structural, dynamic, and energetic mechanisms of RNA homodimerization and strand displacement pathways. The research employs computational...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $773,053 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective June 6, 2025, with a completion date of May 31, 2030. This research project focuses on elucidating the biosynthesis of beta-1,6-glucan in the cell wall of Cryptococcus neoformans, a fungal pathogen responsible for approximately 150,000 deaths annually,...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $899,850 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Whitehead Institute for Biomedical Research, effective February 20, 2026, through January 31, 2031. This award supports fundamental research aimed at elucidating the molecular mechanisms by which apicomplexan parasites recognize and invade host cells—a critical process for parasite survival...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Methodist Hospital Research Institute a Project Grant of $444,125 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 8, 2025, with a completion date of July 31, 2027. This research project will characterize a previously unknown intercellular signaling pathway in Group B Streptococcus (GBS) and determine its contribution to bacterial pathogenesis. Specifically,...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Methodist Hospital Research Institute a $2.47 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026, through March 31, 2030. This award supports fundamental biomedical research aimed at deciphering the activation mechanisms and immune functions of gasdermin C (GSDMC), a protein family member critical to innate immunity and...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 2, 2026, with a completion date of January 31, 2028. The award supports investigator-initiated biomedical research examining viral infection sensing mechanisms in Caenorhabditis elegans (C. elegans), a model organism system. The research will...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $638,220 Project Grant effective April 1, 2026, through March 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports investigator-initiated biomedical research examining DNA ADP-ribosylation mechanisms in bacterial-phage interactions. The research focuses on understanding how bacteria utilize DNA-targeting...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $417,845 to the University of Nebraska Medical Center under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 9, 2025, for a project period extending through June 30, 2027. The award supports research to identify novel immune determinants influencing Staphylococcus aureus biofilm infection using Collaborative Cross (CC) mouse lines. The research addresses gaps in...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $566,875 to the La Jolla Institute for Immunology under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 18, 2026, with a completion date of January 31, 2028. Under this Project Grant, the institute will conduct research to de-orphanize a novel G-protein coupled receptor (GPCR) expressed by tissue-resident memory T cells (TRM cells). The research objective...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $715,894 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 8, 2025, for a five-year research initiative extending through July 31, 2030. This award funds fundamental biomedical research investigating the influence of microbial metabolites on mitosome function in Cryptosporidium parvum, a parasitic pathogen...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $157,500 Project Grant to the University of Missouri at Kansas City (UMKC) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2028. The award supports investigator-initiated research to decode the glycan compositions and structures of glycosylated RNA molecules (GlycoRNA-L and GlycoRNA-S) isolated from leukocytes. These molecules represent a novel class of glycan-modified small non-coding RNAs that localize to cell surfaces and mediate cell-cell interactions and signaling processes. The research deliverables will be generated through two primary methodological approaches: metabolic labeling combined with enzymatic digestion, and purification of GlycoRNA-L and GlycoRNA-S samples followed by liquid chromatography/mass spectrometry (LC/MS) analysis. The project aims to characterize the structural and compositional differences between the two GlycoRNA forms, which are robustly expressed in immune cells but not in non-immune cells, thereby advancing understanding of their functional significance in immune system biology and potentially identifying therapeutic applications in infectious disease and immunologic research domains.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $157.5k | 3/30/26 |