Project Grant R03AG095793
Award Date 9/1/25
Completion Date 8/31/27
Dollars Obligated $423K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New York, USA
Similar Awards
- This $463,625 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) supports research to better understand the effects of aging on the lung adenocarcinoma (LUAD) tumor microenvironment. The Icahn School of Medicine at Mount Sinai will use single-cell RNA sequencing and spatial analysis technologies to characterize age-related cellular and molecular changes in the LUAD tumor microenvironment. This research aims to uncover new therapeutic opportunities to modulate...
- This $789,664 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a research project titled "Dissecting the Cellular and Spatial Tissue Clock of the Human Lung and Peripheral Blood" at the Icahn School of Medicine at Mount Sinai. The project aims to leverage single-cell RNA sequencing and spatial transcriptomics to characterize the effect of age on the cellular microenvironment of the human lung and peripheral blood. The research will...
- This federal Project Grant award of $145,566 from the National Institute on Aging (CFDA 93.866 - Aging Research) is supporting research at the Icahn School of Medicine at Mount Sinai to investigate how the brain accumulates and utilizes "cognitive maps" - internal neural representations that enable flexible behavior and memory recall. The research aims to provide insights into the neuronal coding deficits underlying cognitive decline, with the goal of informing therapeutic...
- This $745,765 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the Icahn School of Medicine at Mount Sinai (ISMMS) in New York aims to investigate the effects of Alzheimer's disease (AD) risk genes and aging on human microglia activity and lipid metabolism. The key focus is on understanding how genetic variants associated with increased AD risk or longevity may impact microglia's ability to clear cholesterol/lipid-rich cellular debris, a critical...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a Project Grant in the amount of $4,035,962.00 to the Icahn School of Medicine at Mount Sinai (ISMMS) on September 15, 2025. The grant is titled "Examining Unique Markers and Risk Factors for AD/ADRD in Foreign- and Native-Born Older Chinese Americans: A Study of Social Determinants of Health, Sleep Patterns, Neuroimaging, and Plasma Biomarkers." The project aims to...
- This Project Grant award from the Department of Health and Human Services' National Institutes of Health (CFDA 93.310 - Trans-NIH Research Support) provides $703,644 to the Icahn School of Medicine at Mount Sinai to investigate the drivers of accelerated aging in people living with HIV (PWH). The research aims to study the effects of HIV and antiretroviral therapy on epigenetic aging and clonal hematopoiesis, as well as examine the role of socio-behavioral factors and genetic predisposition in...
- This federal Project Grant award of $641,856 from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research to determine the effects of reduced nursing home capacity on older adults, their caregivers, and post-acute/long-term care access. The project, which runs from September 1, 2025 to May 31, 2030, will conduct rigorous quantitative analyses to assess the implications of nursing home capacity declines, which have accelerated due to the COVID-19 pandemic. The...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $242,846.00 to the Icahn School of Medicine at Mount Sinai to develop and validate a novel chest CT-based frailty screening tool using artificial intelligence. The goal is to enable opportunistic frailty assessment during routine cardiac imaging procedures in older adults with stable ischemic heart disease, addressing the limited adoption of frailty screening in clinical practice. The project...
- The National Institute on Aging (NIA) awarded a $676,000 Project Grant under its Aging Research Federal Grant Program (CFDA 93.866) to the Icahn School of Medicine at Mount Sinai. The grant will fund research to study the unintended impact of the 2016 CDC opioid prescribing guidelines on disparities in opioid utilization among vulnerable subgroups of older adults, including those with Alzheimer's and related dementias, racial/ethnic minorities, and those experiencing socioeconomic deprivation....
- This $999,975.63 federal Project Grant, awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research by the Icahn School of Medicine at Mount Sinai to investigate the molecular mechanisms behind the increased vulnerability of the APOE4 gene to Alzheimer's disease and identify potential new therapeutic targets. The award period runs from April 1, 2025, to March 31, 2028. The Icahn School of Medicine at Mount Sinai is a leading...