Project Grant R01NS151429
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Drexel University $547,255 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of the functional organization of descending neuron networks that control collision-avoidance behavior. Using electron microscopy connectomes of the central nervous system at synaptic...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded The Medical University of South Carolina $100,228 on December 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on complement-mediated mechanisms of injury and repair in germinal matrix hemorrhage, a leading neurological injury of prematurity....
- The National Institute of Neurological Disorders and Stroke awarded The Johns Hopkins University $232,938 on February 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to generate critical knowledge on neuronal membrane proteasome-derived peptide signaling in the peripheral nervous system. The research extends prior work on NMP-peptides and their role in peripheral neuron crosstalk and regulation. The award funds proteomics,...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, awarded The Johns Hopkins University $119,691 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research understanding how eye movements contribute to spatial navigation in rodents and directional encoding in disease states. The research combines naturalistic behavioral paradigms with...
- The National Institute of Neurological Disorders and Stroke awarded the University of Missouri System $329,234 on June 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research on synaptic function during metabolic stress. The research project, titled "Transforming Synapses to Operate During Extreme Metabolic Dysfunction," investigates how the brain maintains synaptic performance when energy delivery...
- The National Institute of Neurological Disorders and Stroke awarded The Ohio State University $433,125 on May 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and optimize a three-dimensional total internal reflection fluorescence structured illumination microscope (3D TIRF-SIM) for investigating synaptic vesicle exo-endocytosis coupling in living cells. The research addresses a critical gap in neuroscience by...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Oregon Health & Science University $507,491 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) on August 12, 2026. The award funds investigation into the mechanistic basis of astrocyte-neuron signaling during neuronal remodeling in the developing brain. The research uses Drosophila models to understand how...
- The National Institute of Neurological Disorders and Stroke awarded Thomas Jefferson University $195,000 on May 19, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research to map and validate RNA G-quadruplex (GQ) structures at TDP-43-regulated cryptic exons in patient-derived neurons, and to identify and optimize small molecules that selectively bind and stabilize those structures. The research combines...
- The National Institute of Neurological Disorders and Stroke awarded Rush University Medical Center $1.212 million on June 25, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the role of alpha-synuclein phosphorylation in the synucleinopathy olfactory system. The research examines whether phosphorylated alpha-synuclein at serine 129 (PS129) drives early pathogenesis in synucleinopathies within the olfactory system...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded $153,560 to the Broad Institute, Inc. (doing business as Broad Institute of MIT and Harvard) on December 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining how excitatory neurons regulate interneuron fate, position, and survival during...
The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Thomas Jefferson University (operating as Sidney Kimmel Medical College) $509,949 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on the molecular and cellular mechanisms of synaptic growth restriction in central olfactory circuits. The project examines genetic mechanisms that promote and restrict synaptic formation in olfactory sensory circuits—specifically, how olfactory receptor neurons and projection neurons establish and regulate the first synapse of olfactory circuits. The work employs genetic labeling tools, clonal analysis, high-resolution imaging, and biochemical approaches to investigate a novel pathway that restricts excessive synapse formation and to understand how imbalances in synapse promotion and restriction contribute to neurodevelopmental, cognitive, psychiatric, and sensory processing disorders. Performance occurs in Philadelphia, PA. The period of performance extends from September 1, 2026, through May 31, 2031. This is a Project Grant, the standard assistance type for extramural research awards from NINDS.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $509.9k | 8/28/26 |