Project Grant R01NS150750
- The National Institute of Neurological Disorders and Stroke awarded Rutgers, The State University of New Jersey $677,059 on July 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the role of tonic dopamine release in Parkinson's disease motor deficits. The research uses a genetic mouse model lacking synaptojanin1 (SYNJ1) in dopamine neurons to define the molecular basis and network consequences of dopamine...
- The National Institute of Neurological Disorders and Stroke awarded Northwestern University $566,529 on April 24, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate age-related deficits in trophic support of dopamine neurons in preclinical models of Parkinson's disease. The research examines cell-type-specific alterations in LRRK2G2019S mice to determine how the LRRK2 mutation affects neuroprotective signaling...
- The National Institute on Aging awarded Rutgers The State University of New Jersey, School of Nursing, $431,750 on May 15, 2026, under the Aging Research program (CFDA 93.866) to investigate the role of synaptojanin1 (SYNJ1) in age-dependent motor decline. The award funds research examining whether SYNJ1, a synaptic Parkinson's disease gene encoding a lipid phosphatase essential for synaptic membrane trafficking, contributes to normal age-related motor decline and whether targeting SYNJ1 can...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, awarded Rutgers The State University of New Jersey, School of Nursing, $474,749 on August 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the molecular and cellular mechanisms governing functional maturation and adult subtype diversification in spinal motor neurons. The project addresses postnatal...
- The National Institute of Neurological Disorders and Stroke awarded Rutgers The State University of New Jersey $1.872 million on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate fibrinogen-mediated mechanisms in cerebral amyloid angiopathy. The research elucidates molecular mechanisms underlying cerebral amyloid angiopathy, a cerebrovascular pathology affecting over 80 percent of Alzheimer's disease...
- The National Institute of Neurological Disorders and Stroke awarded Rutgers, The State University $118,593 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Assistance Listing). The award funds research investigating the role of dorsal horn interneurons expressing the serotonin 6 receptor (5HTR6+ interneurons) in sensorimotor integration within the spinal cord under both normal conditions and following spinal cord...
- The National Institute of Neurological Disorders and Stroke awarded Rutgers The State University of New Jersey $607,954 on July 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research to identify and validate the chokepoints of epileptogenic networks in mesial temporal lobe epilepsy—specific brain regions where multiple ictogenic pathways converge—to improve surgical outcomes for patients with drug-resistant...
- The National Institute of Neurological Disorders and Stroke awarded Rutgers The State University of New Jersey, doing business as RBHS-School of Nursing, $1.84 million on September 5, 2026, to investigate phosphodiesterase 2A signaling in traumatic brain injury and Alzheimer's disease under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The project examines how phosphodiesterase 2A modulates voltage-dependent anion channel 1...
- The National Institutes of Health Office of the Director awarded $471,000 to Rutgers The State University of New Jersey, doing business as RBHS-School of Nursing, on August 15, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to support Project Grant R01NS144283 investigating astrocyte-based mechanisms of organophosphate poisoning. The award funds research examining how astrocytes—glial cells abundant in the brain—contribute to injury from acute organophosphate exposure,...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $627,103 to the Research Foundation For Mental Hygiene, Inc. on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The Research Foundation For Mental Hygiene, Inc., operating through its New York State Psychiatric Institute division, will investigate the role of the adaptive...
The National Institute of Neurological Disorders and Stroke awarded Rutgers The State University of New Jersey $617,246 on September 26, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the toxicity of lipid-rich alpha-synuclein inclusions in Parkinson's disease pathology. The research examines Lewy bodies and related lipid-rich alpha-synuclein inclusions prevalent in the substantia nigra and brainstem regions. The project tests the hypothesis that the lipid droplet-rich environment of dopaminergic neurons nucleates aberrant liquid-liquid phase separation of alpha-synuclein, producing condensates selectively toxic to mitochondria and driving early energy failure and neurodegeneration in the substantia nigra. The work seeks to identify druggable targets to prevent or reverse lipid-rich alpha-synuclein toxicity. Rutgers, doing business as RBHS-School of Nursing, serves as the recipient and will conduct the work in Newark, New Jersey. The award carries a period of performance from September 26, 2026, through June 30, 2031. The source does not identify sub-recipients.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $617.2k | 8/26/26 |