Project Grant R01NS146474
- The National Institute of General Medical Sciences awarded The Research Foundation For The State University Of New York $153,560 on December 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the role of intrinsically disordered regions in regulating FOXG1-chromatin binding dynamics. The research investigates how intrinsically disordered regions outside the DNA-binding domain of FOXG1, a transcription factor regulating neurodevelopment, influence...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $627,103 to the Research Foundation For Mental Hygiene, Inc. on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The Research Foundation For Mental Hygiene, Inc., operating through its New York State Psychiatric Institute division, will investigate the role of the adaptive...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $440,275 to The Research Foundation for the State University of New York (RF SUNY) on July 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for a two-year project period concluding June 30, 2027. The project, "Systematic Discovery of OLIG2 Upstream Regulators for Central Nervous System Myelination," focuses on...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded $153,560 to the Broad Institute, Inc. (doing business as Broad Institute of MIT and Harvard) on December 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining how excitatory neurons regulate interneuron fate, position, and survival during...
- The National Institute of Neurological Disorders and Stroke awarded Yale University $462,855 under grant R21NS147184 on September 1, 2026, to develop and characterize isogenic neuronal cell models carrying mitochondrial DNA mutations implicated in neurological diseases. The recipient will establish human immortalized neuronal cell lines and induced pluripotent stem cell–derived neurons harboring pathogenic mitochondrial DNA mutations across oxidative phosphorylation complexes I, III, IV, V,...
- The National Institute of Neurological Disorders and Stroke awarded The Trustees of Columbia University in the City of New York $126,900 on March 7, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research to exploit RNA biogenesis, specifically alternative splicing programs, to accelerate maturation of human neurons in vitro and to develop models of age-related tauopathies. The research addresses a fundamental...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded The Medical University of South Carolina $100,228 on December 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on complement-mediated mechanisms of injury and repair in germinal matrix hemorrhage, a leading neurological injury of prematurity....
- The National Institute of Neurological Disorders and Stroke awarded the University of California, San Diego $129,186 on July 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate metabolic plasticity and neuronal resilience in response to chronic mitochondrial DNA damage. The research will characterize mitochondrial DNA distribution and motility in healthy versus mitochondrial DNA-compromised neurons using two...
- The National Institute of Neurological Disorders and Stroke awarded The Research Foundation For The State University Of New York (operating as Stony Brook University) $552,680 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of disrupted striatal cholinergic signaling and compulsive motor behaviors. The research tests a hypothesis that impaired striatal cholinergic signaling...
- The National Institute of Neurological Disorders and Stroke awarded The Research Foundation For The State University Of New York (operating as Stony Brook University) $126,789 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the role of myocyte enhancer factor 2A (MEF2A) in the selective vulnerability of dopamine neurons in Parkinson's disease. The project examines molecular mechanisms underlying...
The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The Research Foundation for the State University of New York $645,070 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating mitochondrial gene regulation in central nervous system development, with focus on how the transcription factor FOXG1 coordinates mitochondrial gene expression, cell cycle progression, and neuronal differentiation in the developing cortex. The research addresses mechanisms underlying neurodevelopmental disorders including FOXG1 syndrome, characterized by microcephaly, corpus callosum agenesis, seizures, and related neurological symptoms. The study examines the hypothesis that FOXG1 and the transcription factor NRF1 cooperatively activate mitochondrial genes during brain development, with implications for understanding how mitochondrial dysfunction contributes to neurodevelopmental and neurodegenerative disorders. The Research Foundation for the State University of New York serves as fiscal agent and sponsored programs administrator for SUNY institutions; the ultimate research performance location is Buffalo, New York. The award period runs from September 1, 2026, through August 31, 2031. This is a Project Grant, the standard assistance type for investigator-initiated research under NINDS's extramural research portfolio.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $645.1k | 8/25/26 |