Project Grant R01NS144393
Award Date 8/1/25
Completion Date 4/30/30
Dollars Obligated $410K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Kansas City, KS 66160, USA
Similar Awards
- This Project Grant award of $1,188,230 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to evaluate the cellular composition, activation state, and spatial niches involved in neuroma formation following severe peripheral nerve injuries. The primary goals are to validate preliminary data indicating that neutrophil extracellular traps (NETs) may be an...
- This $437,250 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will support research to compare the gene expression of the key cell types that form the blood-nerve barrier (BNB) in the peripheral nervous system and the blood-brain barrier (BBB) in the central nervous system under physiological conditions. The research will also...
- This $429,000 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to investigate the role of Schwann cell PIEZO1 in pain sensation. The key objectives are to: 1) develop and validate adeno-associated virus (AAV) vectors for selective inhibition of Schwann cell PIEZO1, and 2) determine the sensory effects of Schwann cell...
- This $764,659 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program supports research to investigate the mechanisms underlying neuropathic spontaneous pain. The key objectives are to characterize the role of local vascular movement in triggering neuropathic spontaneous pain, determine how mechanoreceptors in sensory neurons contribute...
- This $244,815 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research conducted by Brandeis University to provide a systematic mechanistic description of the molecular pathways by which the duration of temperature experience is encoded in the gene expression profile of a specific sensory neuron type (AFD) in the nematode...
- The University of California, San Diego (UCSD) was awarded a $434,500 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The funding will support research to investigate the regulation of Schwann cell mitochondria homeostasis and its role in painful peripheral neuropathy. Specifically, the project aims to examine how the low-density lipoprotein...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is focused on developing a novel drug candidate to treat demyelinating neuropathies. The $352,073 award will support rigorous in vivo testing of the experimental ABCA1 agonist drug, CS6253, in validated mouse models of hereditary peripheral nerve disorders characterized by impaired...
- This federal Project Grant award of $597,999.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the neuronal populations and central sensitization mechanisms underlying mechanical allodynia (a condition where normally innocuous touch becomes painful after injury) in the dorsal horn. The research aims to identify the excitatory...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $377,262 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The University of Kentucky Research Foundation. The grant, awarded on August 15, 2025, supports research to investigate the mechanism underlying sphingoid base-induced neurotoxicity in neurodegenerative diseases. Specifically, the project will use a transgenic mouse model to dissect the...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded Kenyon College a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $454,424 grant, effective April 1, 2025 through March 31, 2028, aims to characterize the cellular and molecular mechanisms of Schwann cell demyelination and identify factors that promote peripheral remyelination using a novel larval zebrafish model. The project will test...